DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5883 and pear1

DIOPT Version :9

Sequence 1:	NP_648526.2	Gene:	CG5883 / 39352	FlyBaseID:	FBgn0036225	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	405	Identity:	81/405 - (20%)
Similarity:	123/405 - (30%)	Gaps:	162/405 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GSCSES---IICQNFESTPGITCSGSKPYYSKSKGSCQASADTYCDTSKICKGSGT-----GYIG 104
            |.|:::   .:|:  :...|..|..|.|...:....|.      |....||:|:|.     |::|
Zfish   198 GICNQTTGECVCK--QGFTGTLCEESCPRPKRCAARCP------CQNGGICQGNGVCLCPPGWMG 254

  Fly   105 DT-----------INCA------NWYYCDADALLGKGTCNLGMYFDQVSKSC---VYSEDT--VC 147
            ..           |||:      |..:||.:.  |:..|:.|...::.::.|   .|.||.  ||
Zfish   255 PVCTERCPPGRFGINCSKDCLCHNGGHCDQEK--GQCQCDAGYTGERCNEECPVGTYGEDCKGVC 317

  Fly   148 -----AAKYEI--------------CD------------------VAPVGT----PFRDDANCHK 171
                 |..|.|              ||                  ..|:.|    |.:.:..|..
Zfish   318 DCANGARCYNIHGGCLCEPGFKGPRCDHRMCPEAVFGMHCQHRCLCNPLNTLSCHPLKGECTCQP 382

  Fly   172 YYT---CSSKSLVENTCENGLYYNVATGTCVRKKDVICENHPLPDEVCGN------------KKL 221
            .:.   |:      .||..|.|.|.....|      :|.|..:.|.|.|.            :||
Zfish   383 GWAGLYCN------ETCAQGYYGNGCLEPC------LCVNGGVCDSVTGQCHCPPGFTGLHCEKL 435

  Fly   222 AVRNKFVSD--MATCR-----------GYYYCRDLGSGIPDTDPIYQQCDENNFFNQERQACMPR 273
            . .:.|...  ::.|:           |...|::...| ||..   ..|.|..:.....:.|...
Zfish   436 C-EDGFYGKGCLSACKCVNSIVCSPVDGACICKEGWRG-PDCS---IACSEGTWGPGCNRTCKCT 495

  Fly   274 ESQKCDYDRCDGR---KDGFEVAEID----------GCHHYIECV--DGRET-----------TP 312
            ....|  |..||.   ..|:..|..|          ||.:..:||  :|.|:           |.
Zfish   496 NGASC--DPADGSCKCTAGWRGASCDEPCLIGTFGPGCQNQCDCVHDEGCESVTGQCLCLPGWTG 558

  Fly   313 ISCEDKYFDVVTQNC 327
            :.|        ||.|
Zfish   559 VRC--------TQQC 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5883	NP_648526.2	CBM_14	95..146	CDD:279884	18/77 (23%)
CG5883	NP_648526.2	CBM_14	154..204	CDD:279884	13/74 (18%)
pear1	XP_700533.4	EMI	29..96	CDD:284877
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482	7/40 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010