DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5883 and Megf11

DIOPT Version :9

Sequence 1:	NP_648526.2	Gene:	CG5883 / 39352	FlyBaseID:	FBgn0036225	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_006511049.1	Gene:	Megf11 / 214058	MGIID:	1920951	Length:	1138	Species:	Mus musculus

Alignment Length:	338	Identity:	72/338 - (21%)
Similarity:	97/338 - (28%)	Gaps:	140/338 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 SCSESIICQNFESTPGITCSGSKPYYSKSKGSCQASADTYCDTSKICKGSGTGYIGDT------- 106
            :|:|:.||.|     |..||   |:    .|||..:               .|::||:
Mouse   487 NCNETCICAN-----GAACS---PF----DGSCACT---------------PGWLGDSCELPCPD 524

  Fly   107 ----INCANWYYCD------ADALLG-------------KGTCNLGMYFDQVSKSCVYSEDTVCA 148
                :||:.  :||      .|.:.|             ..||..|.:....|.||.......|:
Mouse   525 GTFGLNCSE--HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCS 587

  Fly   149 AKYEICDVAPVGTPFRDDANCHKYYTCSSKSLVENTCENGLYYNVAT---GTCVRKK------DV 204
            .:...|:.||   .||.             .|.:..|..|.|.:...   ..||..:      ..
Mouse   588 PEDGSCECAP---GFRG-------------PLCQRICPPGFYGHGCAQPCPLCVHSRGPCHHISG 636

  Fly   205 ICENHP-----LPDEVCGNKKLAVRNKFVSDMATCRGYYYCRDLGSGIPDTDPIYQQCDENNFFN 264
            |||..|     |.::||..      ..|..|   |.....|.:.|:    ..||...|.
Mouse   637 ICECLPGFSGALCNQVCAG------GHFGQD---CAQLCSCANNGT----CSPIDGSCQ------ 682

  Fly   265 QERQACMPRE-----SQKCD--------YDRCDGRKDGFEVAEIDGCHHYIECVDGRETTPISCE 316
                 |.|..     ||.|.        :..|.........||...||    |..|  .|.:.|
Mouse   683 -----CFPGWIGKDCSQACPSGFWGSACFHTCSCHNGASCSAEDGACH----CTPG--WTGLFC- 735

  Fly   317 DKYFDVVTQNCSS 329
                   ||.|.|
Mouse   736 -------TQRCPS 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5883	NP_648526.2	CBM_14	95..146	CDD:279884	15/80 (19%)
CG5883	NP_648526.2	CBM_14	154..204	CDD:279884	11/58 (19%)
Megf11	XP_006511049.1	EMI	25..92	CDD:400092
		EGF_CA	188..233	CDD:419698
		EGF_CA	274..319	CDD:419698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010