DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt4R and RPT4A

DIOPT Version :9

Sequence 1:	NP_001287039.1	Gene:	Rpt4R / 39351	FlyBaseID:	FBgn0036224	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_199115.1	Gene:	RPT4A / 834316	AraportID:	AT5G43010	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	391	Identity:	292/391 - (74%)
Similarity:	342/391 - (87%)	Gaps:	5/391 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TD-DERVR----ALTNYRTKLLEHREIESKLKALRDKYKVVNAEYEKSEDDLKALQSVGQMVGEI 69
            || ||.||    |::.||.|||:|:|:||:::..|:..:....|:.|:|||||:||||||::||:
plant     2 TDVDESVRRRTAAVSEYRKKLLQHKELESRVRTARENLRGAKKEFNKTEDDLKSLQSVGQIIGEV 66

  Fly    70 LKQLTPDNFIVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVDPLVYNMTHE 134
            |:.|..:..|||||:|||||||||.:::||||..||||.||:|||||||.|||||||:||||.||
plant    67 LRPLDNERLIVKASSGPRYVVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREVDPVVYNMLHE 131

  Fly   135 DPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKTLLARAIASQ 199
            ||||::|:.:||||.|||||||.|||||:||::||||||.||||.|||||||||||||||||||.
plant   132 DPGNISYSAVGGLGDQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASN 196

  Fly   200 MDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQR 264
            :||||||||||||:|||||||||||||||.|||:|||||||||||||||||||||||||||||||
plant   197 IDANFLKVVSSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSADREIQR 261

  Fly   265 TLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMDILKIHAEPL 329
            ||||||||:||||.||:|||||||||||.||||||||||||||:|||||||.:|||||||||..:
plant   262 TLMELLNQLDGFDNLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRMDILKIHAAGI 326

  Fly   330 NKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIADNKKLESRLD 394
            .|.|||||||:|||::.||||||||||||||:||:|.:|::||.|||||||||:::.|||||...
plant   327 AKHGEIDYEAIVKLAEGFNGADLRNICTEAGMFAIRAERDYVIHEDFMKAVRKLSEAKKLESSSH 391

  Fly   395 Y 395
            |
plant   392 Y 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4R	NP_001287039.1	RPT1	13..396	CDD:224143	289/387 (75%)
Rpt4R	NP_001287039.1	AAA	180..312	CDD:278434	121/131 (92%)
RPT4A	NP_199115.1	RPT1	17..390	CDD:224143	284/372 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	253	1.000	Domainoid score	I507
eggNOG	1	0.900	-	-		E1_COG1222
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	621	1.000	Inparanoid score	I207
OMA	1	1.010	-	-		QHG53508
OrthoDB	1	1.010	-	-		D571919at2759
OrthoFinder	1	1.000	-	-		FOG0003819
OrthoInspector	1	1.000	-	-		mtm1097
orthoMCL	1	0.900	-	-		OOG6_101751
Panther	1	1.100	-	-	O	PTHR23073
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2663
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840