Protein Alignment Rpt4R and PSMC3

DIOPT Version :10

• Sequence 1: NP_648525.1
• Gene: Rpt4R / 39351
• FlyBaseID: FBgn0036224
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_002795.2
• Gene: PSMC3 / 5702
• HGNCID: 9549
• Length: 439
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 164/403 - (40%)
• Similarity: 240/403 - (59%)
• Gaps: 38/403 - (9%)

  Fly    22 RTKLLEHR---------EIESKLKALRDKYKVVNAEYEKSEDDLKALQSVGQMVGEILKQLTPD- 76
            ||:||:..         .:..:|:|::||.|      |.|| .:|..:::..:|..:::.|..|
Human    44 RTRLLDSEIKIMKSEVLRVTHELQAMKDKIK------ENSE-KIKVNKTLPYLVSNVIELLDVDP 101

  Fly    77 --------NF-----------IVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPR 122
                    |.           ::|.|....|.:.....::.||||||..|.::..:..|:..||.
Human   102 NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPT 166

  Fly   123 EVDPLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGT 187
            |.|..|..|..::.....|::||||.:||:||.|.|.||:.:.:.|..:||.||||.|:||||||
Human   167 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGT 231

  Fly   188 GKTLLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRF 252
            ||||||||.|:|..|.|||:....:|..:||:.|:|:|:.||.|::..|.|||:||:||||.:||
Human   232 GKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRF 296

  Fly   253 SEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVA 317
            ....:.|||:|||::|||||:|||....|||:|.||||.|.|||||||.||||||:|.|:|||.|
Human   297 DSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEA 361

  Fly   318 RMDILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRK 382
            |..|::||:..:|...:::||.:.:.:|.||||..:.:|.|||:.|||.....:..||:|:.:.:
Human   362 RARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILE 426

  Fly   383 IADNKKLESRLDY 395
            :...||  :.|.|
Human   427 VQAKKK--ANLQY 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4R	NP_648525.1	PRK03992	13..388	CDD:179699	160/394 (41%)
PSMC3	NP_002795.2	PRK03992	39..432	CDD:179699	160/394 (41%)