Protein Alignment Rpt4R and PSMC2

DIOPT Version :9

• Sequence 1: NP_001287039.1
• Gene: Rpt4R / 39351
• FlyBaseID: FBgn0036224
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_002794.1
• Gene: PSMC2 / 5701
• HGNCID: 9548
• Length: 433
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 167/399 - (41%)
• Similarity: 246/399 - (61%)
• Gaps: 26/399 - (6%)

  Fly    11 DDERVRALTNYRTKLL----------EHREIESKLKALRDKYKVVNAEYEKSED----------- 54
            ||:.:|||......||          :.:::|..::.|..|...:....|....
Human    18 DDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAA 82

  Fly    55 DLKALQSVGQM-VGEILKQLTPDN----FIVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTL 114
            |.:.|||...: |....|.:..|:    :|:......::||....|:....::.|.||.:|....
Human    83 DKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKY 147

  Fly   115 TIMRYLPREVDPLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGC 179
            .|...||.::||.|..|..|:..:|.|:::||..:||.:||||:|.|||:|:.|:.:||.||||.
Human   148 QIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212

  Fly   180 LLYGPPGTGKTLLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEI 244
            ||:|||||||||.|||:|::.||.|::|:.|.:|.||:||.||::||:|..||..:.|:||.|||
Human   213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEI 277

  Fly   245 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLE 309
            |||||.||.:|...|.|:|||::||:||:||||..|.:|::|||||||||||||:||||||||:|
Human   278 DAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIE 342

  Fly   310 IPLPNEVARMDILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQE 374
            ..||:...|..|.||||..::...:|.:|.:.:|.....||::|::|||||:||:|..|:...::
Human   343 FSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEK 407

  Fly   375 DFMKAVRKI 383
            ||::||.|:
Human   408 DFLEAVNKV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4R	NP_001287039.1	RPT1	13..396	CDD:224143	165/397 (42%)
		AAA	180..312	CDD:278434	83/131 (63%)
PSMC2	NP_002794.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		2/3 (67%)
		RPT1	23..430	CDD:224143	165/394 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920