DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt4R and psmc1b

DIOPT Version :9

Sequence 1:	NP_001287039.1	Gene:	Rpt4R / 39351	FlyBaseID:	FBgn0036224	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001002091.1	Gene:	psmc1b / 415181	ZFINID:	ZDB-GENE-040625-69	Length:	440	Species:	Danio rerio

Alignment Length:	393	Identity:	172/393 - (43%)
Similarity:	246/393 - (62%)	Gaps:	19/393 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PLANPPTDDERVRALTNYRTK---LLEHREI--ESKLKALRDKYKVVNAEYEKSE-DDLKAL-QS 61
            ||..|.|.. |::.|...|.|   |:|...|  :.::|.|.:|     .|.|:|: |||:.. .|
Zfish    50 PLVTPHTQC-RLKLLKQDRIKDYLLMEEEFIRNQEQMKPLEEK-----QEEERSKVDDLRGTPMS 108

  Fly    62 VGQMVGEILKQLTPDNF-IVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVD 125
            ||     .|:::..||. ||..|.|..:.|.....::|:.|:||..|.|:.....::..|..:.|
Zfish   109 VG-----TLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTD 168

  Fly   126 PLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKT 190
            |||..|..|......||:||||..||:|::|.:||||.:|:.:..:||.||||.:|||.||||||
Zfish   169 PLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGAPGTGKT 233

  Fly   191 LLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEG 255
            |||:|:|:|..|.||:||.|.::.||:|:..:|:||:|..|.:|.|.|:|:|||||||.:|:...
Zfish   234 LLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSN 298

  Fly   256 TSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMD 320
            :..:||||||::|||||:||||:.|.||:||||||.:||||||:||||:|||:|.|||:|..:..
Zfish   299 SGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRR 363

  Fly   321 ILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIAD 385
            |.:||...:....::..:.::...|..:|||::.|||||||.|||..|..|..|||.|:...:..
Zfish   364 IFQIHTSRMTVAEDVSLDDLILAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLY 428

  Fly   386 NKK 388
            .|:
Zfish   429 KKQ 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4R	NP_001287039.1	RPT1	13..396	CDD:224143	168/384 (44%)
Rpt4R	NP_001287039.1	AAA	180..312	CDD:278434	79/131 (60%)
psmc1b	NP_001002091.1	PTZ00361	1..440	CDD:185575	172/393 (44%)
		Prot_ATP_ID_OB	108..>176	CDD:293059	23/72 (32%)
		AAA	222..355	CDD:278434	79/132 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920