DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt4R and Psmc1

DIOPT Version :9

Sequence 1:	NP_001287039.1	Gene:	Rpt4R / 39351	FlyBaseID:	FBgn0036224	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_476464.1	Gene:	Psmc1 / 117263	RGDID:	621097	Length:	440	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	173/393 - (44%)
Similarity:	247/393 - (62%)	Gaps:	19/393 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PLANPPTDDERVRALTNYRTK---LLEHREI--ESKLKALRDKYKVVNAEYEKSE-DDLKAL-QS 61
            ||..|.|.. |::.|...|.|   |:|...|  :.::|.|.:|     .|.|:|: |||:.. .|
  Rat    50 PLVTPHTQC-RLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEK-----QEEERSKVDDLRGTPMS 108

  Fly    62 VGQMVGEILKQLTPDNF-IVKASNGPRYVVGCRRQINKEKLKPGTRVALDVTTLTIMRYLPREVD 125
            ||     .|:::..||. ||..|.|..:.|.....::|:.|:||..|.|:.....::..|..:.|
  Rat   109 VG-----TLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTD 168

  Fly   126 PLVYNMTHEDPGNVNYAEIGGLGQQIRELREVIELPLLNPDIFLRVGISPPKGCLLYGPPGTGKT 190
            |||..|..|......||:||||..||:|::|.:||||.:|:.:..:||.||||.:||||||||||
  Rat   169 PLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKT 233

  Fly   191 LLARAIASQMDANFLKVVSSAIVDKYIGESARLIREMFAYARDHQPCIIFMDEIDAIGGRRFSEG 255
            |||:|:|:|..|.||:||.|.::.||:|:..:|:||:|..|.:|.|.|:|:|||||||.:|:...
  Rat   234 LLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSN 298

  Fly   256 TSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRLDRKLEIPLPNEVARMD 320
            :..:||||||::|||||:||||:.|.||:||||||.:||||||:||||:|||:|.|||:|..:..
  Rat   299 SGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363

  Fly   321 ILKIHAEPLNKRGEIDYEAVVKLSDLFNGADLRNICTEAGLFALRCDREFVIQEDFMKAVRKIAD 385
            |.:||...:....::..:.::...|..:|||::.|||||||.|||..|..|..|||.|:...:..
  Rat   364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLY 428

  Fly   386 NKK 388
            .|:
  Rat   429 KKQ 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4R	NP_001287039.1	RPT1	13..396	CDD:224143	169/384 (44%)
Rpt4R	NP_001287039.1	AAA	180..312	CDD:278434	80/131 (61%)
Psmc1	NP_476464.1	PTZ00361	1..440	CDD:185575	173/393 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..104		9/24 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920