Protein Alignment byn and Tbx19

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_114394.1
• Gene: Tbx19 / 83993
• MGIID: 1891158
• Length: 446
• Species: Mus musculus
• Alignment Length: 517
• Identity: 206/517 - (39%)
• Similarity: 254/517 - (49%)
• Gaps: 155/517 - (29%)

  Fly    78 GSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQI 142
            |.|.|  :.|:|.|:|..||.||:.:||||||||||||||||:|||.:||||.|||::||:||:.
Mouse    32 GDPTE--KQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVRT 94

  Fly   143 DSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTNGNGQIMLNS 207
            ||||||||||||||.||.||...:.:|:||:||||||||||.||||:|||||||.||.|||||||
Mouse    95 DSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNS 159

  Fly   208 LHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKER---- 268
            ||||||:||:||||...|.|:...||||||||||||||||:|:||||||||||||||||||
Mouse   160 LHKYEPQVHIVRVGGAHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLK 224

  Fly   269 --PDTL--YPHDTHY---GWLIPPPTHYTAAAAA---VAAPPPLSIAQSHGLVASCPSVSSAESV 323
              |:.:  ..|.|:.   ||::..|.....||.:   .|.|.||....:|
Mouse   225 DVPEAISESQHVTYSHLGGWILSNPDGVCTAANSNYQYATPLPLPAPHTH--------------- 274

  Fly   324 GPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHS 388
                 ..|:.|.      .:...|..||                         |||     .:|.
Mouse   275 -----HGCEHYA------GLRGHRQAPY-------------------------PSA-----YMHR 298

  Fly   389 TSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATS 453
            ..:.||:...|||:...:.|.|.:           :.|:.::|.||:.|.|.|        |...
Mouse   299 NHSPSVNLIESSSNNLQVFSGPDS-----------WTSLSSTPHASILSVPHS--------NGPI 344

  Fly   454 VPGPMPMNVCSGRNISSHNSPSP-----TNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTG 513
            .|||               ||.|     :||
Mouse   345 NPGP---------------SPYPCLWTISNG---------------------------------- 360

  Fly   514 VGVGGGAGTTGSPQAAYGAAAHQVYHPTPTSPTHQLYTNA-------VLNAPSALSYSASGW 568
               |||...:||...|..:....:.:|..|||:..|.|.|       ||..||..|.:.|.|
Mouse   361 ---GGGPVASGSEVHASTSGTILLGNPAVTSPSSLLPTQATTSAGVEVLGEPSLTSIAVSTW 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	136/181 (75%)
Tbx19	NP_114394.1	TBOX	39..221	CDD:214656	137/181 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	290	1.000	Domainoid score	I1543
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2467
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002920
OrthoInspector	1	1.000	-	-		otm43478
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4488
SonicParanoid	1	1.000	-	-		X2738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.950