Protein Alignment byn and EOMES

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001265111.1
• Gene: EOMES / 8320
• HGNCID: 3372
• Length: 705
• Species: Homo sapiens
• Alignment Length: 562
• Identity: 179/562 - (31%)
• Similarity: 246/562 - (43%)
• Gaps: 136/562 - (24%)

  Fly    18 GNVSGGGGGGGAGGGAGSGSPQHVTHNGHGHGHGLGGVAAVSGGGASVSGNGGHRVVGGAGSPNE 82
            |..:|.|.||.:|||.|.|:.|: :.....:|...|..||.|.||           :||.|.|..
Human   211 GAGAGSGAGGSSGGGGGPGTYQY-SQGAPLYGPYPGAAAAGSCGG-----------LGGLGVPGS 263

  Fly    83 LDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRW 147
            ..| ..:.|.:|.|||:|.....|||:||.||||||.:..:.:||:|.|.|.|.:|.|..|.:.|
Human   264 GFR-AHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHW 327

  Fly   148 KYVNGEWVPGGKAE-VPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNK---TNGNGQ-IMLNS 207
            ::..|:||..|||: ....|.:||||||||.|:|||::.|||.|:||||.   .|.|.| |:|.|
Human   328 RFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQS 392

  Fly   208 LHKYEPRVHLVRVG-------SEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDA 265
            ||||:||:|:|.|.       :|.....|:.|.||||||||||||.::|.|||.:|||||.|.|.
Human   393 LHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDN 457

  Fly   266 KERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGS 330
            .:                   :.|||:......|.|....:||.:|               .||
Human   458 YD-------------------SMYTASENDRLTPSPTDSPRSHQIV---------------PGG- 487

  Fly   331 CDRYGRSLSSRSVAP---TRTTP----YSRPRVVSGSGSNGSAGNASSTSPQPPSAPQ----TPT 384
              |||    .:|..|   ..|.|    |:..|.|  ..:||......|.....|  ||    ||.
Human   488 --RYG----VQSFFPEPFVNTLPQARYYNGERTV--PQTNGLLSPQQSEEVANP--PQRWLVTPV 542

  Fly   385 SLHSTSTGSVSTSVSSSSGG-----GIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQS 444
            ....|:...:|:..|..:..     ||.|.|    ..:|:|    :.....||   |...:.|..
Human   543 QQPGTNKLDISSYESEYTSSTLLPYGIKSLP----LQTSHA----LGYYPDPT---FPAMAGWGG 596

  Fly   445 NGNY---------WNATSVPGPMPMNVCSGRNISS-------HNSPS----PTNGSPSYTTS--- 486
            .|:|         |.:.:.|.....:..|...:..       ...||    .:|.|..||::
Human   597 RGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKR 661

  Fly   487 ---SPSYTIHHLTP-------HSHQYNMAQTDIYGTGVGVGG 518
               |||.:.:..:|       ::.:|:.      .|..|:||
Human   662 RRLSPSNSSNENSPSIKCEDINAEEYSK------DTSKGMGG 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	95/193 (49%)
EOMES	NP_001265111.1	TBOX	267..460	CDD:238106	95/211 (45%)
		T-box_assoc	482..703	CDD:292794	54/259 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810