Protein Alignment byn and tbx21

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001164070.1
• Gene: tbx21 / 797797
• ZFINID: ZDB-GENE-080104-3
• Length: 609
• Species: Danio rerio
• Alignment Length: 702
• Identity: 194/702 - (27%)
• Similarity: 275/702 - (39%)
• Gaps: 219/702 - (31%)

  Fly    21 SGGGGGGGAGGGAGSGSPQHVTHNGHGHGH---GLGGVAAVSGGGASVSGNGGHRVVGGAGSPN- 81
            |.|...|.....|..||....:.:|.||.:   |....::.:|.....|...|:......|.|.
Zfish    73 SAGAQTGRFYAPAPLGSCHFTSRSGTGHTYVPAGADAYSSANGKDVYPSSADGYTASFQHGFPRA 137

  Fly    82 --------ELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLE 138
                    ::....::.|::..||.:|.....|||:||.||||||.:..:.:.|||:|.|.:.::
Zfish   138 PMYSLPGLQVSGKTQVLLNNYPLWAKFHKYQTEMIITKQGRRMFPFLSFNITSLDPSAHYNIYVD 202

  Fly   139 FVQIDSHRWKYVNGEWVPGGKAE-VPPSNPIYVHPESPNFGAHWMKEPISFAKVKLT-NKTNGNG 201
            .|..|.|.|:|..|:||..|||| ..|.|.:|:||:|||.|.|||::.:||.|:||| ||.:.|.
Zfish   203 VVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDSPNTGTHWMRQEVSFGKLKLTNNKGSSNN 267

  Fly   202 ---QIMLNSLHKYEPRVHLVRV---GSEQRHVV----TYPFPETQFIAVTAYQNEEVTSLKIKYN 256
               .|:|.|||||:||:|:|.|   |:|...:.    |:.||||||||||||||.::|.|||.:|
Zfish   268 VAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQTFVFPETQFIAVTAYQNADITQLKIDHN 332

  Fly   257 PFAKAFLDAKERPDTLY-PHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSA 320
            ||||.|   ::..|||| |.|...  |.|.||                  :|..|::
Zfish   333 PFAKGF---RDNYDTLYAPPDPDR--LTPSPT------------------ESQQLLS-------- 366

  Fly   321 ESVGPSSGGSCDRYGRSLSSRSVAP-TRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPT 384
                    |||..:...||.:.::| .::..|||..|             |.|.|    .|:.||
Zfish   367 --------GSCYPHQPYLSDQYMSPLPQSRFYSREPV-------------SMTQP----CPKDPT 406

  Fly   385 SLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFS-YPSSWQSNGNY 448
            |                      |..|....||..|        ..|....|| |.:.:.||..|
Zfish   407 S----------------------SPHSRWYLSSQQA--------VPPNRLDFSAYETEYTSNSLY 441

  Fly   449 WNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTG 513
                                    .|.|...||           ||  |.|:......|.  |..
Zfish   442 ------------------------KPFPLQSSP-----------HH--PLSYYSENPFTS--GAV 467

  Fly   514 VGVGGGAGT-TGSPQAAYGAAAHQVYHPTPTSPTHQLYTNAVLNAPSALS---YSASGWHNGSGA 574
            .....||.| :|.|...|      :.||..:.||..|.....:.:|:|.|   .:.|.:|
Zfish   468 SSANPGAWTASGRPSPQY------LNHPHHSKPTSSLSWFRAVPSPAASSSPTATNSRFH----- 521

  Fly   575 EYGLYQNAAAAYYQPEYIPLEIGYATHPLEPVDVSKTLDDPQAAMYKPSDEQGSVITLECASSSL 639
                   |:.:..:|:..||                 |.|                      .|.
Zfish   522 -------ASPSLLEPQRQPL-----------------LQD----------------------KSK 540

  Fly   640 KSSHDIKIESSSLE--HAGERGTVGGGAA----VVSVPTAVVNGAPAVAADT 685
            :|:.|..||:.|::  .:.:.|...||.:    |....::..|..|..:|:|
Zfish   541 ESTEDTWIEAPSVKSVDSADSGLFEGGESKKRRVSPYTSSTENSPPNRSAET 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	92/188 (49%)
tbx21	NP_001164070.1	T-box_TBX21	150..340	CDD:410329	92/192 (48%)
		T-box_assoc	363..608	CDD:465042	76/389 (20%)