Protein Alignment byn and TBX6

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_004599.2
• Gene: TBX6 / 6911
• HGNCID: 11605
• Length: 436
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 134/388 - (34%)
• Similarity: 187/388 - (48%)
• Gaps: 91/388 - (23%)

  Fly    89 ISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGE 153
            :||::||||..|.::..|||:||.||||||..::|.:||||.|.|..||:.:.:|..|:::....
Human    93 LSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRR 157

  Fly   154 WVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKT-NGNGQIMLNSLHKYEPRVHL 217
            |.|.||||....:.:|:||:||..|||||::|:||.:|||||.| :.:|.::|:|:|||:||:||
Human   158 WEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHL 222

  Fly   218 VRVGSE-QRH---VVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLD-----AKER----- 268
            ||.... .:|   :.::.||||.||:||||||.::|.|||..|||||.|.:     .:||
Human   223 VRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVK 287

  Fly   269 -----PDTLY------------PHDTHYGWLI--------PPPTHYTAAAAAVAAPPP-----LS 303
                 |:...            |.|:..|..|        |.|...|||.|.:...|.     |.
Human   288 RKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLH 352

  Fly   304 IAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGN 368
            .|..||..:..|:.|.:....|.||                  |:.|||...:....||.||...
Human   353 PAAFHGAPSHLPTRSPSFPEAPDSG------------------RSAPYSAAFLELPHGSGGSGYP 399

  Fly   369 ASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASP 431
            |:     ||:.|..|..|.                ||....|.|       |..|::.|.:.|
Human   400 AA-----PPAVPFAPHFLQ----------------GGPFPLPYT-------APGGYLDVGSKP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	89/188 (47%)
TBX6	NP_004599.2	TBOX	90..277	CDD:238106	89/183 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..339		13/67 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..379		5/36 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810