Protein Alignment byn and TBX5

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_016875401.1
• Gene: TBX5 / 6910
• HGNCID: 11604
• Length: 534
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 162/507 - (31%)
• Similarity: 231/507 - (45%)
• Gaps: 98/507 - (19%)

  Fly    87 LRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVN 151
            :::.|.:|||||:|..:..|||:||.||||||..|:..:||:|...|.:|::.|..|.||:|:.:
Human    70 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFAD 134

  Fly   152 GEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRV 215
            .:|...||||......:||||:||..|||||::.:||.|:||||. .:..|.|:|||:|||:||:
Human   135 NKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRL 199

  Fly   216 HLVRV------GSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAF------------ 262
            |:|:.      ||:.....|:.||||.|||||:|||.::|.|||:.|||||.|
Human   200 HIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMS 264

  Fly   263 -LDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPS 326
             :.:||.|            ::|..|            ....:|.:|.     |..|.:.::..|
Human   265 RMQSKEYP------------VVPRST------------VRQKVASNHS-----PFSSESRALSTS 300

  Fly   327 SG-GS---CDRYGRSLSSRSVAPTRTTPYSRPRVVSG-SGSNGSAGNASSTSPQPPSAPQTPTSL 386
            |. ||   |:. |.|..|:.:.|. ..||..|:..|. ...........||:..|...|...||
Human   301 SNLGSQYQCEN-GVSGPSQDLLPP-PNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETS- 362

  Fly   387 HSTSTGSVSTSVSSSSGGGIG----SAPSTGCFSSSYAQSGFMSVDASPTASVFSYP----SSWQ 443
            .|.......:|.....|.|..    ||....|.   ||.|      |.|:..|.|..    ::|.
Human   363 PSEEDSFYRSSYPQQQGLGASYRTESAQRQACM---YASS------APPSEPVPSLEDISCNTWP 418

  Fly   444 SNGNYWNATSVPGPMPMNVCSGRNISSHNSPSP---------TNGSPSYTTSSPSYTIHHLTPHS 499
            |..:|.:.| |....||:....::.|:|.:..|         .:|||.....    ...|.|..:
Human   419 SMPSYSSCT-VTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEG----MFQHQTSVA 478

  Fly   500 HQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHPTPTSPTHQLYT 551
            ||..:.|.   |...|: ...||...|:..|   :|.|  |...|| ||.::
Human   479 HQPVVRQC---GPQTGL-QSPGTLQPPEFLY---SHGV--PRTLSP-HQYHS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	90/200 (45%)
TBX5	XP_016875401.1	TBOX	69..257	CDD:238106	89/186 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810