Protein Alignment byn and TBX1

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_016884414.1
• Gene: TBX1 / 6899
• HGNCID: 11592
• Length: 545
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 169/608 - (27%)
• Similarity: 231/608 - (37%)
• Gaps: 176/608 - (28%)

  Fly     3 TSHILSAVDPTTGLSGNVSGGGGGGG-----------------AGGGAGSGSPQHVTHNGHGHGH 50
            |:..||::....|..|..|.|....|                 |.|..|...|.|........|.
Human    64 TASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGA 128

  Fly    51 GLGGVAAVSGGGASVSGNGGHRVVGGAGSP---NELDRNLRISLDDRELWLRFQNLTNEMIVTKN 112
            .....|...|.|||.:        ..|.:|   |.....:.:.|:.:.||..|..|..||||||.
Human   129 ATSAAAEPEGPGASCA--------AAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKA 185

  Fly   113 GRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYV--NGEWVPGGKAEVPPSNP--IYVHPE 173
            ||||||..::...|:||.|.|.:|::||.:|..|::|.  :..|:..|||:  |:.|  ::.||:
Human   186 GRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKAD--PATPGRVHYHPD 248

  Fly   174 SPNFGAHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRVHLV----RVGSE---QRHVVTY 230
            ||..||.|||:.:||.|:||||. .:.||.|:|||:|:|:||.|:|    |..||   :.:..|:
Human   249 SPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTF 313

  Fly   231 PFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAA 295
            .|.||:|.|||||||..:|.|||..|||||.|.|..       |.|    |   |..|...|...
Human   314 VFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCD-------PED----W---PRNHRPGALPL 364

  Fly   296 VAAPPPLSIAQSHGLVAS--CPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVS 358
            ::|     .|:|...|||  .||.:..::.........|..|.::......|    |....||:|
Human   365 MSA-----FARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAHP----PQLLARVLS 420

  Fly   359 GS--GSNGSAG-----NASSTSPQPPS------APQTPTSLHSTSTGSVSTSVSSSSGGGIGSAP 410
            .|  |:.|:.|     .|....|.||:      ||.....||.
Human   421 PSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHH---------------------- 463

  Fly   411 STGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPS 475
                                   ..:.||::  :..:|..|.|.|.|.|:....|.....|..|
Human   464 -----------------------HPYKYPAA--AYDHYLGAKSRPAPYPLPGLRGHGYHPHAHP- 502

  Fly   476 PTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHP 540
                             ||   |.|..                      ||.||..|||
Human   503 -----------------HH---HHHPV----------------------SPAAAAAAAA------ 519

  Fly   541 TPTSPTHQLYTNAVLNAPSALSY 563
            ...:....:|::|....|.:..|
Human   520 AAAAAAANMYSSAGAAPPGSYDY 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	88/193 (46%)
TBX1	XP_016884414.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810