Protein Alignment byn and TBXT

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001353214.1
• Gene: TBXT / 6862
• HGNCID: 11515
• Length: 436
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 214/485 - (44%)
• Similarity: 260/485 - (53%)
• Gaps: 103/485 - (21%)

  Fly    78 GSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQI 142
            |.|.|  |.||:.|::.||||||:.|||||||||||||||||:|::.|||||.|||:.||:||..
Human    35 GDPTE--RELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAA 97

  Fly   143 DSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTNGNGQIMLNS 207
            |:|||||||||||||||.|....:.:|:||:||||||||||.|:||:|||||||.||.|||||||
Human    98 DNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNS 162

  Fly   208 LHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKERPD-- 270
            |||||||:|:||||..||.:.::.||||||||||||||||:|:||||||||||||||||||.|
Human   163 LHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHK 227

  Fly   271 --TLYPHDTHY-------GWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPS 326
              ...|.|:..       |||:|        ..:...||    |..|      |....|.|: ||
Human   228 EMMEEPGDSQQPGYSQSGGWLLP--------GTSTLCPP----ANPH------PQFGGALSL-PS 273

  Fly   327 SGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHSTST 391
            : .|||||....|.||      :||..|.    :..|.|          |..:..:|..|
Human   274 T-HSCDRYPTLRSHRS------SPYPSPY----AHRNNS----------PTYSDNSPACL----- 312

  Fly   392 GSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQ-SNGNYWNATSVP 455
             |:..|..:.|..|:.:.||...          :|.:|||..|...|||.|. |||     ...|
Human   313 -SMLQSHDNWSSLGMPAHPSMLP----------VSHNASPPTSSSQYPSLWSVSNG-----AVTP 361

  Fly   456 GPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTD---IYGTGVGVG 517
            |.....|.:|......      .|||:           |.||.:|..:...:.   :|      .
Human   362 GSQAAAVSNGLGAQFF------RGSPA-----------HYTPLTHPVSAPSSSGSPLY------E 403

  Fly   518 GGAGTTGSPQAAYGAAA--HQVYHPTPTSP 545
            |.|..|....:.|.|||  ..:...||.||
Human   404 GAAAATDIVDSQYDAAAQGRLIASWTPVSP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	131/176 (74%)
TBXT	NP_001353214.1	T-box_TBXT	41..219	CDD:410328	131/177 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..309		10/48 (21%)