Protein Alignment byn and tbx2

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001030291.1
• Gene: tbx2 / 619588
• XenbaseID: XB-GENE-1018115
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 175/645 - (27%)
• Similarity: 255/645 - (39%)
• Gaps: 141/645 - (21%)

  Fly    55 VAAVSGGGASVSGNGGH------RVVGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNG 113
            :|..:..|..||..|.|      |.:.......|::.:.:::|:.:|||.:|..|..||::||:|
 Frog    57 LAGAAEAGLHVSALGHHHQAAHLRSLKSLEPEEEVEDDPKVTLEAKELWDQFHKLGTEMVITKSG 121

  Fly   114 RRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFG 178
            |||||..|:..||||..|.|.:|::.|..|..|:|:.|..|:..|||:......:|:||:||..|
 Frog   122 RRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATG 186

  Fly   179 AHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRVHLVRVG-------SEQRHVVTYPFPET 235
            ..||.:|::|.|:||||. ::.:|..:|||:|||:||.|:||..       |..|   ||.||||
 Frog   187 EQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFR---TYVFPET 248

  Fly   236 QFIAVTAYQNEEVTSLKIKYNPFAKAFLDA-----KERPDTLYPH---------------DTHYG 280
            .|||||||||:::|.|||..|||||.|.|.     ::|.....|.               ::...
 Frog   249 DFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLSLPSLRMYEEQCKADRDGAESDAS 313

  Fly   281 WLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSL-SSRSVA 344
            ...|.|...:..:.....|.||.:.:|          :..|..|..|....||  |.: ::||.:
 Frog   314 SCDPAPGRDSLHSPLSTEPSPLRLHRS----------NREEKFGADSDQELDR--REVRTARSHS 366

  Fly   345 PT-RTTPYSRPRVVS-GSGSNGSAGNASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGG-- 405
            |. ..:|.|.||:.. |...|           .|....::|.|.........|.|:....|..
 Frog   367 PVGHRSPPSSPRLEDRGKDKN-----------TPEKKSESPESRKDGGDNVFSRSLEKDKGESRR 420

  Fly   406 ---IGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRN 467
               ..|.|..|..|........:..|:.|..|
 Frog   421 KEDSKSDPECGSLSKETFAPLMVQTDSPPHLS--------------------------------- 452

  Fly   468 ISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVG------VGGGA---GTT 523
             :||......:|.......:|......|..|..|:.|........|:|      .|..|   |:.
 Frog   453 -ASHLQSLALSGLHGQQFFNPLNAAQPLFIHPGQFTMGPGAFSAMGMGHLLASMTGASALDNGSL 516

  Fly   524 GSPQAAYGAAA---HQVYH-------PTPT----SPTHQLYTNAVLNAPSALSYSASGWHNGSGA 574
            .|.|.|.|||.   |...|       |.|.    .|....|..|...|.||:.        .:.|
 Frog   517 SSVQGATGAATFPFHLSQHMLASQGIPMPAFGGLFPYPYTYMAAAAAAASAMP--------ATSA 573

  Fly   575 EYGLYQNAAAA------YYQPEYIPLEIGYATHPLEPVDVSKTLDDPQAAMYKPSDEQGS 628
            ...:.:|...:      .:.|..||:.|..:|: |....:|.:| :|.:...||...:.|
 Frog   574 ATTMPRNPFLSSTRPRLRFNPYQIPVGIPPSTN-LLTTGLSASL-NPGSESSKPGSSRES 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	87/184 (47%)
tbx2	NP_001030291.1	T-box_TBX2_3-like	96..277	CDD:410314	87/183 (48%)
		T-box	99..277		87/180 (48%)
		TBX	295..371	CDD:432659	15/87 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	606..660		7/28 (25%)