Protein Alignment byn and Tbx21

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_062380.2
• Gene: Tbx21 / 57765
• MGIID: 1888984
• Length: 530
• Species: Mus musculus
• Alignment Length: 556
• Identity: 166/556 - (29%)
• Similarity: 226/556 - (40%)
• Gaps: 157/556 - (28%)

  Fly     9 AVDPTTGLSGNVSGGGGGGGAGGGAGSGSPQHVTHNGHGHGHGLGG--------VAAVSGGG--- 62
            |.|||...:|:..|....|||...|..             |..||.        ||...|.|
Mouse    41 AQDPTDRRAGSSLGTPYSGGALVPAAP-------------GRFLGSFAYPPRAQVAGFPGPGEFF 92

  Fly    63 ASVSGNGGHRVVGGAGSPN-------------------ELDRNLRISLDDRELWLRFQNLTNEMI 108
            ...:|..|:..|.|..:|:                   |:...||::|.:..||.:|.....|||
Mouse    93 PPPAGAEGYPPVDGYPAPDPRAGLYPGPREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMI 157

  Fly   109 VTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAE-VPPSNPIYVHP 172
            :||.||||||.:..:.:||:|.:.|.:.::.|.:|.|.|:|.:|:||..|||| ..|.|.:||||
Mouse   158 ITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHP 222

  Fly   173 ESPNFGAHWMKEPISFAKVKLTN----KTNGNGQIMLNSLHKYEPRVHLVRV---------GSEQ 224
            :|||.|||||::.:||.|:||||    ..|....|:|.|||||:||:|:|.|         .:..
Mouse   223 DSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSASN 287

  Fly   225 RHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPH-DTHYGWLIPPP-- 286
            .||.|  |.||||||||||||.|:|.|||..|||||.|   :|..:::|.. ||.    :|.|
Mouse   288 THVFT--FQETQFIAVTAYQNAEITQLKIDNNPFAKGF---RENFESMYASVDTS----VPSPPG 343

  Fly   287 ----------------THYTAAAA-----------AVAAPPPLSIAQSHGLVASCPSVSSAESVG 324
                            ..|...:.           .::.|..|...:.|...|...:||...::.
Mouse   344 PNCQLLGGDPFSPLLSNQYPVPSRFYPDLPGQPKDMISQPYWLGTPREHSYEAEFRAVSMKPTLL 408

  Fly   325 PSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHST 389
            ||                 ||..|.||.|.:.|...|:..            |.|||.|..:  :
Mouse   409 PS-----------------APGPTVPYYRGQDVLAPGAGW------------PVAPQYPPKM--S 442

  Fly   390 STGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSV 454
            ..|......:.....|:||:...|                       |.||.|.      ..||:
Mouse   443 PAGWFRPMRTLPMDPGLGSSEEQG-----------------------SSPSLWP------EVTSL 478

  Fly   455 -PGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPS 489
             |.|....:..|.......||.|::|..|....:||
Mouse   479 QPEPSDSGLGEGDTKRRRISPYPSSGDSSSPAGAPS 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	94/190 (49%)
Tbx21	NP_062380.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		5/13 (38%)
		T-box_TBX21	135..325	CDD:410329	94/194 (48%)
		T-box_assoc	<393..520	CDD:465042	39/182 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..530		21/100 (21%)