Protein Alignment byn and Tbx3

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_853669.1
• Gene: Tbx3 / 353305
• RGDID: 735203
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 196/715 - (27%)
• Similarity: 279/715 - (39%)
• Gaps: 181/715 - (25%)

  Fly    54 GVAAVSGGGASVSGNGGHRVVGGA--GSP-------------------NELDRNLRISLDDRELW 97
            |.||:|..|| ::.....::||.|  |.|                   .:::.:.::.|:.:|||
  Rat    50 GAAALSLPGA-LAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELW 113

  Fly    98 LRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEV 162
            .:|.....||::||:||||||..|:..||||..|.|.:|::.:..|..|:|:.|..|:..|||:.
  Rat   114 DQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADP 178

  Fly   163 PPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTN-----------------GN----GQIMLN 206
            .....:|:||:||..|..||.:.::|.|:||||..:                 ||    .|.:||
  Rat   179 EMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILN 243

  Fly   207 SLHKYEPRVHLVRVG-------SEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLD 264
            |:|||:||.|:||..       |..|   ||.||||:|||||||||:::|.|||..|||||.|.|
  Rat   244 SMHKYQPRFHIVRANDILKLPYSTFR---TYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305

  Fly   265 A------KERPDTLYP-------HDTHYGWLIPPPTHYTA-AAAAVAAPPPLSIAQSHGLVASCP 315
            .      |.:..||..       |....|......:...| ...|.|:.|.:|...:..|...||
  Rat   306 TGNGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCP 370

  Fly   316 S-------VSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTS 373
            |       ..|.|..||.   :||          .|...||....|     ....||....:...
  Rat   371 SEAESDAEAESKEEHGPE---ACD----------TAKISTTTAEEP-----GRDKGSPATRAQLF 417

  Fly   374 PQPPSAPQ--------TPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMS--VD 428
            |..||..:        :|.|.||.:|.|.||.|.     |.....|.|       :.|.:|  ||
  Rat   418 PAEPSRARDTARLDKASPDSRHSPATISSSTRVP-----GADEHRSPG-------REGPVSAKVD 470

  Fly   429 ---ASPTASVFSYPSSWQSNGNYWNATSVPGPMP-MNVCSGRNISSHNSPSPTNGSPSYTTSSPS 489
               |.|....|: |.|.|::.   .|....||:| :....|                  ......
  Rat   471 EARALPAKDAFA-PLSVQTDA---TAHLTQGPLPGLGFAPG------------------LAGQQF 513

  Fly   490 YTIHHLTPHSHQYNMA-------------QTDIYGTGVGVGG----GAGTTGSPQAAYGAAA--- 534
            :..|.|..|..|:.|.             ...:.|...||.|    ...:..:.|...||:|
  Rat   514 FNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATL 578

  Fly   535 --HQVYHPTPT-----SPTHQL--YTNAVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPE 590
              |...|...:     ||...|  |....:.|.:|.|.:|:    .|......:.|..:...:..
  Rat   579 PFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAA----SSSVHRHPFLNLNSMRPRLR 639

  Fly   591 YIPLEIGYATHPLEPVDVSKTLDDPQAAMYK---PSDEQGSVITLECASSSLKSSHDIKIESSSL 652
            |.|..|     |:...|.|..|.....:|..   |.|.:.:|:....||.::.|..::...||:|
  Rat   640 YSPYSI-----PVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTL 699

  Fly   653  652
              Rat   700  699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	86/204 (42%)
Tbx3	NP_853669.1	T-box_TBX2_3-like	101..305	CDD:410314	86/206 (42%)
		TBX	323..404	CDD:432659	21/98 (21%)
		DUF5585	336..>686	CDD:465521	89/410 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..467		29/125 (23%)