Protein Alignment byn and TBX10

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_011543294.1
• Gene: TBX10 / 347853
• HGNCID: 11593
• Length: 430
• Species: Homo sapiens
• Alignment Length: 354
• Identity: 116/354 - (32%)
• Similarity: 166/354 - (46%)
• Gaps: 81/354 - (22%)

  Fly    62 GASVSGNGGHRVV--GGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISA 124
            |...|..|...|.  .|.|..|.....:.:.|:.:.||..|..|..||||||.||||||..::..
Human    83 GPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKI 147

  Fly   125 SGLDPAAMYTVLLEFVQIDSHRWKYV--NGEWVPGGKAEVPPSNP--IYVHPESPNFGAHWMKEP 185
            .|:|..|.|.:|::|:.:|..|::|.  :..|:..|||:  |:.|  ::.||:||..||.||::.
Human   148 LGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKAD--PATPGRVHFHPDSPAKGAQWMRQI 210

  Fly   186 ISFAKVKLTNK-TNGNGQIMLNSLHKYEPRVHLV----RVGSE---QRHVVTYPFPETQFIAVTA 242
            :||.|:||||. .:.||.|:|||:|:|:||.|:|    |..||   |.:..::.|.||||.||||
Human   211 VSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQENFKSFIFTETQFTAVTA 275

  Fly   243 YQNEEVTSLKIKYNPFAKAF----LDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLS 303
            |||..:|.|||..|||||.|    ||:               |             .||..|.||
Human   276 YQNHRITQLKIASNPFAKGFRESDLDS---------------W-------------PVAPRPLLS 312

  Fly   304 I-AQSHGLVASC-----------PSVSSAES------------------VGPSSGGSC---DRYG 335
            : |:||..::.|           |:.:||.:                  :.|::....   ..|.
Human   313 VPARSHSSLSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQSLYS 377

  Fly   336 RSLSSRSVAPTRTTPYSRPRVVSGSGSNG 364
            .:.|...:..||..||..|.:.:.....|
Human   378 GAPSHLGIPRTRPAPYPLPNIRADRDQGG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	87/197 (44%)
TBX10	XP_011543294.1	TBOX	110..300	CDD:238106	85/191 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810