Protein Alignment byn and Tbx5

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001009964.1
• Gene: Tbx5 / 304514
• RGDID: 1305702
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 164/585 - (28%)
• Similarity: 224/585 - (38%)
• Gaps: 220/585 - (37%)

  Fly    87 LRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVN 151
            :::.|.:|||||:|..:..|||:||.||:|||..|:..:||:|...|.:|::.|..|.||:|:.:
  Rat    54 IKVFLHERELWLKFHEVGTEMIITKAGRQMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFAD 118

  Fly   152 GEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRV 215
            .:|...||||......:||||:||..|||||::.:||.|:||||. .:..|.|:|||:|||:||:
  Rat   119 NKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRL 183

  Fly   216 HLVRV------GSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAF------------ 262
            |:|:.      ||:.....|:.||||.|||||:|||.::|.|||:.|||||.|
  Rat   184 HIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDLELHRMS 248

  Fly   263 -LDAKERPDTLYPHDT-------HYGW-----------------------------LIPPPTHYT 290
             :.:||.|  :.|..|       |..:                             |:|||.
  Rat   249 RMRSKEYP--VVPRSTVRHKVANHSPFSSETRALSTSSNLGSQYQCENGVSGPSQDLLPPPN--- 308

  Fly   291 AAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPR 355
                      |..:||.|..:..|......|         |.             :...||.:|.
  Rat   309 ----------PYPLAQEHSQIYHCTKRKDEE---------CS-------------STEHPYKKPY 341

  Fly   356 VVSGSGSNGSAGNASSTSPQPPSA------PQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGC 414
            :              .|||.....      ||..         .:|||..:.      ||....|
  Rat   342 M--------------ETSPSEEDTFYRSGYPQQQ---------GLSTSYRTE------SAQRQAC 377

  Fly   415 FSSSYAQSGFMSVDASPTASVFSYP----SSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPS 475
            .   ||.|      |.|:..|.|..    ::|.|..:|.:.| |....||:....::.|:|
  Rat   378 M---YASS------APPSEPVPSLEDISCNTWPSMPSYSSCT-VTTVQPMDRLPYQHFSAH---- 428

  Fly   476 PTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHP 540
                    .||.|      |.|..                  .|....||||...|...||
  Rat   429 --------FTSGP------LVPRL------------------AGMANHGSPQLGEGMFQHQ---- 457

  Fly   541 TPTSPTHQ-----------------------LYTNAVLNAPSALS----YSASG------WHNGS 572
              ||.|||                       |||:.|   |..||    :|..|      |...|
  Rat   458 --TSVTHQPVVRQCGPQTGLQSPGSLQPPEFLYTHGV---PRTLSPHQYHSVHGVGMVPEWSENS 517

  Fly   573  572
              Rat   518  517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	89/200 (45%)
Tbx5	NP_001009964.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46
		TBOX	53..241	CDD:238106	88/186 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..313		6/55 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..369		11/73 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810