Protein Alignment byn and Tbx2

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001388735.1
• Gene: Tbx2 / 303398
• RGDID: 1311014
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 171/601 - (28%)
• Similarity: 239/601 - (39%)
• Gaps: 173/601 - (28%)

  Fly    51 GLGGVAAVSGGGASVSGNGGHRVVGGAGSP-------------NELDRNLRISLDDRELWLRFQN 102
            ||.|.||.:...|:.:..|.|....|...|             :|::.:.:::|:.:|||.:|..
  Rat    56 GLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHK 120

  Fly   103 LTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNP 167
            |..||::||:||||||..|:..||||..|.|.:|::.|..|..|:|:.|..|:..|||:......
  Rat   121 LGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKR 185

  Fly   168 IYVHPESPNFGAHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRVHLVRVG-------SEQ 224
            :|:||:||..|..||.:|::|.|:||||. ::.:|..:|||:|||:||.|:||..       |..
  Rat   186 MYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTF 250

  Fly   225 RHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDA----KERP-----DTLYPHDTH-- 278
            |   ||.||||.|||||||||:::|.|||..|||||.|.|.    :|:.     .||..::.|
  Rat   251 R---TYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPTLRLYEEHCK 312

  Fly   279 ---------YGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRY 334
                     .....|||......:.: |||.||.:.::......|.:.|..|........:....
  Rat   313 PERDGAESDASSCDPPPAREPPPSPS-AAPSPLRLHRARAEEKPCAADSDPEPERSGEERAAAPL 376

  Fly   335 GRSLSSRSVAPTRTT--PYSRPRVVSGSGS-----NGSAGNASSTS------------------- 373
            ||| |||..:|.|.|  ..||.|.....||     .|..|..|..|
  Rat   377 GRS-SSRDASPARLTEPERSRERRSPERGSKEPTEGGGDGPFSLRSLEKERAEARRKDEGRKDVG 440

  Fly   374 --PQPPSAP---QT---------------------------------PTSLH------------S 388
              .:|..||   ||                                 |..||            :
  Rat   441 EGKEPSLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFAMGPGAFSA 505

  Fly   389 TSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATS 453
            ...|.:..||:...|...|:||.|.        :|..:....|.||                |.|
  Rat   506 MGMGHLLASVAGGGGNSGGAAPGTA--------AGLDAGGLGPAAS----------------AAS 546

  Fly   454 VPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGG 518
            ...|.|.:: |...::|...|.||.|.              |.|:.:.|..|            .
  Rat   547 TATPFPFHL-SQHMLASQGIPMPTFGG--------------LFPYPYTYMAA------------A 584

  Fly   519 GAGTTGSPQAAYGAAA 534
            .|..:..|..:..|||
  Rat   585 AAAASALPATSAAAAA 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	87/184 (47%)
Tbx2	NP_001388735.1	T-box_TBX2_3-like	103..287	CDD:410314	87/186 (47%)
		TBX	305..379	CDD:432659	13/74 (18%)