Protein Alignment byn and tbx2b

DIOPT Version :10

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_571126.1
• Gene: tbx2b / 30253
• ZFINID: ZDB-GENE-990726-27
• Length: 687
• Species: Danio rerio
• Alignment Length: 683
• Identity: 187/683 - (27%)
• Similarity: 268/683 - (39%)
• Gaps: 173/683 - (25%)

  Fly    50 HGLGGVAAVSGGGASVSGN--GGH-RVVGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTK 111
            |.|.| ||.:|...::|.:  ..| |.:.......|::.:.:::|:.::||.:|..|..||::||
Zfish    55 HTLAG-AAEAGLHPALSHHHQAAHLRSLKSLEPEEEVEDDPKVTLEAKDLWDQFHKLGTEMVITK 118

  Fly   112 NGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPN 176
            :||||||..|:..:|||..|.|.:|::.|..|..|:|:.|..|:..|||:......:|:||:||.
Zfish   119 SGRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPA 183

  Fly   177 FGAHWMKEPISFAKVKLTNK-TNGNGQIMLNSLHKYEPRVHLVRVG-------SEQRHVVTYPFP 233
            .|..||.:|::|.|:||||. ::.:|..:|||:|||:||.|:||..       |..|   ||.||
Zfish   184 TGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFR---TYVFP 245

  Fly   234 ETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDA------KERPDTLYPHDTHYGWLIPPPTHYTAA 292
            ||.|||||||||:::|.|||..|||||.|.|.      |.:..||
Zfish   246 ETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTL-------------------- 290

  Fly   293 AAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSR-PRV 356
                   |.|.:.:....|....:.|.|.|..|::|.........:||    |.|....|| .:.
Zfish   291 -------PSLRMYEDQCKVDRDGADSDASSSEPTTGRDAGHSPGPVSS----PLRFNRGSRDDKT 344

  Fly   357 VSGS-----GSNGSAGNASSTSPQP------------------------PSAPQTPTS------- 385
            .:.|     ..|...|.:||.:|:|                        |.:.:|..|
Zfish   345 CTDSEHEMDHQNDRCGGSSSPAPKPSSPFRSRSEDWGREKPIAEKKDDYPDSRKTSDSIFSIRNL 409

  Fly   386 ----LHSTSTGSVSTSVSSSSGGGI-GSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSN 445
                |.|.|.....:|...:...|| ||..|   ||....|:      .||
Zfish   410 EKDKLESRSRKDTDSSKKDTENSGISGSKDS---FSPLMVQT------ESP-------------- 451

  Fly   446 GNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIY 510
             :::.|    |.:.....||.:.....:|..| |.|             |..|..|:.||.....
Zfish   452 -SHFGA----GHLQSLALSGLHSQQFFNPLNT-GQP-------------LLFHPGQFAMAPGAFS 497

  Fly   511 GTGVG-----VGGGAGTTGSPQAAYGAAA-------HQVYH-------PTPT----SPTHQLYTN 552
            ..|:|     |.|..|......:|.|..:       |...|       |.||    .|....|..
Zfish   498 AMGMGHLLASVSGAGGLENGSLSAQGTGSTPSPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMA 562

  Fly   553 AVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPEYIPLEIGYATHPLEPVDVSKTLDDPQA 617
            |...|.|||..|:|...:.|...:..........:.|..:|:.|..:|:.|       |...|..
Zfish   563 AAAAAASALPASSSTASSLSRNPFLSSSTRPRLRFNPYQLPVSIPQSTNLL-------TTGLPSG 620

  Fly   618 AMYKPSDEQGSVITLECASSSLKSSHDIKIESS 650
              ..||.|..     :|.|.......|.|..:|
Zfish   621 --LNPSSESS-----KCGSREASPVPDHKSGAS 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	85/184 (46%)
tbx2b	NP_571126.1	T-box_TBX2_3-like	95..276	CDD:410314	85/183 (46%)
		TBX	294..361	CDD:432659	14/70 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..452		35/176 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..687		11/50 (22%)