DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment byn and Tbx15

DIOPT Version :9

Sequence 1:	NP_524031.2	Gene:	byn / 39349	FlyBaseID:	FBgn0011723	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001382004.1	Gene:	Tbx15 / 295315	RGDID:	1308094	Length:	602	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	154/503 - (30%)
Similarity:	236/503 - (46%)	Gaps:	89/503 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GGAGS-PNELD--RNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVL 136
            |.||| |..:.  ..:::.|...:||.||.::..|||:||.||||||.:::..:||||...|.:.
  Rat    98 GAAGSVPVAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIA 162

  Fly   137 LEFVQIDSHRWKYV--NGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLT-NKTN 198
            ::.|.:|:.|::||  :.:|:..|.|:.|....:|:||:|...|..||::.:||.|:||| |:.:
  Rat   163 MDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELD 227

  Fly   199 GNGQIMLNSLHKYEPRVHLVR--------------VGSEQRHVVTYPFPETQFIAVTAYQNEEVT 249
            ..|.|:|:|:|||:||||::|              ||.   .|.|:.||||.|..||||||:::|
  Rat   228 DQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGD---GVKTFNFPETVFTTVTAYQNQQIT 289

  Fly   250 SLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPP------------------PTHYTAAAAAV 296
            .|||..|||||.|.|:......|......|.:..||                  .|..:.:.::.
  Rat   290 RLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPSTSST 354

  Fly   297 AAPPPLSIAQSHGLVASC--PSVSSAE---SVGPSSGGSCDRYGRSLS-----SRS-VAPTRTTP 350
            ..|.|  .|.||.|..||  |:...|.   :||......|:   .:||     :|| :|..::.|
  Rat   355 GTPSP--SASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCN---LNLSDYPPCARSNMAALQSYP 414

  Fly   351 YSRPRVVSGSGSNG-SAGNASSTSPQPPSAPQTPTSLHS---TSTGSVSTSVSSSSGGGIGSAPS 411
                 .:|.||.|. .:|.||:|.|.....||...||.|   |.....|.|...:.||.:||.|:
  Rat   415 -----GLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPT 474

  Fly   412 TGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGP----------MPMNVCSGR 466
            :   ...|......:..:|.:..:|......||:   :||.|:..|          .|....|..
  Rat   475 S---QFQYVMQAGNAASSSSSPHMFGGSHMQQSS---YNAFSLHNPYNLYGYNFPTSPRLAASPE 533

  Fly   467 NISSHNS----PSPTNGS---PSYTTSSPSYTIHHLTPHSHQYNMAQT 507
            .:|:..|    .||:||:   ..|..:...:::|.::|.::......|
  Rat   534 KLSASQSTLLCSSPSNGAFGERQYLPTGMEHSVHMISPSTNNQQATNT 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	82/198 (41%)
Tbx15	NP_001382004.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810