Protein Alignment byn and MGA

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_005254300.1
• Gene: MGA / 23269
• HGNCID: 14010
• Length: 3115
• Species: Homo sapiens
• Alignment Length: 677
• Identity: 167/677 - (24%)
• Similarity: 249/677 - (36%)
• Gaps: 171/677 - (25%)

  Fly    74 VGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLE 138
            |||          :.::||:..:|..|.:.:.|||:||.||||||..:...:|||....|.::::
Human    72 VGG----------ITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMD 126

  Fly   139 FVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKT-NGNGQ 202
            ...:|:||:|:....|.|.||||......:::|||||:.|.:||.:|:||.|:||||.| :..|.
Human   127 ISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGH 191

  Fly   203 IMLNSLHKYEPRVHLV---------RVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPF 258
            |:|:|:|:|.||:|||         ::.....|  |:.||:|:|.|||||||.::|.|||.||||
Human   192 IILHSMHRYLPRLHLVPAEKAVEVIQLNGPGVH--TFTFPQTEFFAVTAYQNIQITQLKIDYNPF 254

  Fly   259 AKAFLD--AKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAE 321
            ||.|.|  ...:|                                    |..|
Human   255 AKGFRDDGLNNKP------------------------------------QRDG------------ 271

  Fly   322 SVGPSSGGSCDRYGRSLSSRS-------------VAPTRTTPYSRPRVVSGSGSNGSAGNASSTS 373
                ....|.|:.|.::||.|             :.|....|.||....||.|
Human   272 ----KQKNSSDQEGNNISSSSGHRVRLTEGQGSEIQPGDLDPLSRGHETSGKG------------ 320

  Fly   374 PQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSY 438
                 ..:|..::.....|.:.|..:.|....:....|....:||:.       |.|..||..
Human   321 -----LEKTSLNIKRDFLGFMDTDSALSEVPQLKQEISECLIASSFE-------DDSRVASPL-- 371

  Fly   439 PSSWQSNGNYWNATSVPGPM-----PMNVC-SGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTP 497
                ..||:: |......|:     .:..| .|..:....:...|:   .|:.|.....:.....
Human   372 ----DQNGSF-NVVIKEEPLDDYDYELGECPEGVTVKQEETDEETD---VYSNSDDDPILEKQLK 428

  Fly   498 HSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYH-PTPTSPTHQLYTNAVLNAPSAL 561
            ..::.:..:.|          ...:...|.:..|.|..:::. .|...|...|...||..:...:
Human   429 RHNKVDNPEAD----------HLSSKWLPSSPSGVAKAKMFKLDTGKMPVVYLEPCAVTRSTVKI 483

  Fly   562 SYSASGWHNGSGAEYGLYQNAAAAYYQPEYI------------PLEIGYATH--PLEPVDVSKTL 612
            |.......:.|..:..  ...|...|.|.||            ..|.|...|  .|..|.....|
Human   484 SELPDNMLSTSRKDKS--SMLAELEYLPTYIENSNETAFCLGKESENGLRKHSPDLRVVQKYPLL 546

  Fly   613 DDPQAAMYKPSDEQGSVITLECASSSLKSSHDIKIESSSLEHAG-ERGTVGGGAAVVSVPTAVVN 676
            .:||   :|..|...|:.|......|..|..|   ..|..|..| :|.|:...|....|..|..|
Human   547 KEPQ---WKYPDISDSISTERILDDSKDSVGD---SLSGKEDLGRKRTTMLKIATAAKVVNANQN 605

  Fly   677 GAPAVAADTWTPL--------TPPQST 695
            .:|.|......|.        .||::|
Human   606 ASPNVPGKRGRPRKLKLCKAGRPPKNT 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	82/193 (42%)
MGA	XP_005254300.1	TBOX	74..264	CDD:238106	83/201 (41%)
		DUF4801	1041..1087	CDD:292677
		HLH	2475..2525	CDD:278439

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820