Protein Alignment byn and Tbr1

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_033348.2
• Gene: Tbr1 / 21375
• MGIID: 107404
• Length: 681
• Species: Mus musculus
• Alignment Length: 586
• Identity: 165/586 - (28%)
• Similarity: 250/586 - (42%)
• Gaps: 163/586 - (27%)

  Fly    70 GHRVVG------GAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLD 128
            ||...|      .:..|..:....::.|.:|.|||:|.....|||:||.||||||.:..:.||||
Mouse   181 GHSYQGAPFYQFSSTQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLD 245

  Fly   129 PAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEV-PPSNPIYVHPESPNFGAHWMKEPISFAKVK 192
            |.|.|.:.::.:..|.:.|::..|:|||.|||:. ...|.:|:||:|||.|||||::.|||.|:|
Mouse   246 PTAHYNIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLK 310

  Fly   193 LTNK---TNGNGQ-IMLNSLHKYEPRVHLVRVG-------SEQRHVVTYPFPETQFIAVTAYQNE 246
            |||.   :|.||| ::|.|||||:||:|:|.|.       |:...|.|:.||||||||||||||.
Mouse   311 LTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNT 375

  Fly   247 EVTSLKIKYNPFAKAFLDAKERPDTLY-----------PHDTHYGWLIPPPTHYTAAAAAVAAPP 300
            ::|.|||.:|||||.|   ::..||:|           |:|:....::|      .|..|:|.
Mouse   376 DITQLKIDHNPFAKGF---RDNYDTIYTGCDMDRLTPSPNDSPRSQIVP------GARYAMAG-- 429

  Fly   301 PLSIAQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGS 365
              |..|.. .|::..........|...|...|              |:.|:          :||.
Mouse   430 --SFLQDQ-FVSNYAKARFHPGAGAGPGPGTD--------------RSVPH----------TNGL 467

  Fly   366 AGNASSTSPQPPSAPQ----TP--------TSLHSTST---GSVSTSVSSSSGGGIGSAPSTGCF 415
            .....:..|..|| ||    ||        .|.:.|:|   |:.:|.:
Mouse   468 LSPQQAEDPGAPS-PQRWFVTPANNRLDFAASAYDTATDFAGNAATLL----------------- 514

  Fly   416 SSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNG- 479
              |||.:|..::                             |:....|:||.:..:..||....
Mouse   515 --SYAAAGVKAL-----------------------------PLQAAGCTGRPLGYYADPSGWGAR 548

  Fly   480 SPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHPTPTS 544
            ||.....:.|.::....|:|   ..|...:.|....:|         :.|.|.||.:    :|.:
Mouse   549 SPPQYCGAKSGSVLPCWPNS---AAAAARMAGANPYLG---------EEAEGLAAER----SPLA 597

  Fly   545 PTHQ------LYTNAVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPEYIPLEIGYATHPL 603
            |..:      |..::.:..||::....|       ::.|:|:.|......|...|  :..::.||
Mouse   598 PAAEDAKPKDLSDSSWIETPSSIKSIDS-------SDSGIYEQAKRRRISPADTP--VSESSSPL 653

  Fly   604 E 604
            :
Mouse   654 K 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	95/193 (49%)
Tbr1	NP_033348.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..83
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	108..127
		TBOX	203..396	CDD:238106	95/195 (49%)
		T-box_assoc	418..679	CDD:374412	61/346 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..483		11/60 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..655		12/67 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810