Protein Alignment byn and tbx6

DIOPT Version :9

• Sequence 1: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_705952.2
• Gene: tbx6 / 192294
• ZFINID: ZDB-GENE-020416-5
• Length: 874
• Species: Danio rerio
• Alignment Length: 777
• Identity: 200/777 - (25%)
• Similarity: 303/777 - (38%)
• Gaps: 214/777 - (27%)

  Fly    79 SPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQID 143
            ||.....::|:.|::..||.:|..:..||||||.||||||.:::..|||:|:..|.:||:.|.:|
Zfish    54 SPATPQDSVRMELENAGLWKQFSTVGTEMIVTKKGRRMFPQLRVKLSGLNPSLRYILLLDIVPVD 118

  Fly   144 SHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKT-NGNGQIMLNS 207
            |.|:::.:..|...|.||....:.:::||:||..|.||....|||.:.||||.| :..|.|:|:|
Zfish   119 SSRYRFQDNSWQVVGGAEARLPDRVFIHPDSPATGEHWQNRTISFHRAKLTNNTLDAQGYIILHS 183

  Fly   208 LHKYEPRVHLVRVGSEQRHVV-------TYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLD- 264
            ||:|:||||::    |.|.|:       ::.|||||||.||||||.::|.|||..|||||.|.:
Zfish   184 LHRYQPRVHVI----EARDVLMWGRTQHSFTFPETQFITVTAYQNNKITELKINSNPFAKGFREN 244

  Fly   265 ----AKERP-----------------DTLYPHDTHYGWLIPPPTHYTAAAAAVA-APPPLSIAQS 307
                .|:|.                 ::..|.|:..  |:|......::|..:. ...|::.:..
Zfish   245 GMNCKKQREARLKRKITSSQEECLDIESCDPCDSTE--LLPQSVDLPSSALTIMNTALPITDSGF 307

  Fly   308 HGLVASCPSVSSAE-----------SVGPSSGGS--------------CDRYGR----------- 336
            |..|:|.|..:.::           |..|||..|              .|..|:
Zfish   308 HTEVSSHPDQTDSDQTLVLEQAFLTSEMPSSMESQQQTTSETNVNNALMDETGQMMDLSGYTSSF 372

  Fly   337 ---SLSSRSVAPTRTTPYSRPRVVSGSGSNG----SAGNASSTSPQP-----PSA---------- 379
               .|||.:..|..::.||   |||.:.|:.    .|.:.||....|     |||
Zfish   373 PTPQLSSHTSVPQSSSMYS---VVSSTQSSDLELPQASSISSPHSMPAYSSIPSAEYPGVNSSTA 434

  Fly   380 -PQTPTSL--------HSTSTGSVSTS-------VSSSSGGGIGSAPSTGCFSSSYA-------- 420
             |.:.|||        ||||:..:.:|       ...|........|:...|.|..|
Zfish   435 MPASTTSLSDSYPSISHSTSSHLLQSSSYHSLLPTDQSQDNLSPHTPTNPPFQSIPACQGTRLTI 499

  Fly   421 QSGFMSVD--------------ASPTASVFSYPSSWQSNGNYWNATSVPGP-------MPMNVCS 464
            .||...||              .:||.:.|.:|....:|.        |.|       :|.:...
Zfish   500 DSGQNQVDDGGLSSANATTPAVPNPTQTAFPFPPVQPNND--------PDPTSPSCQSLPQSALP 556

  Fly   465 GRNISSHN---SPSPTNGSPS---------------YTTSSPSYTIHHLTPHSHQYNMAQTDIYG 511
            .:.:|..|   :||..|.:|:               ..:|:|:.|.....|...|.|::.:....
Zfish   557 YQQVSQCNQIPTPSDPNTTPTAFPFPPSEQSTPNSIMVSSNPNTTAFPFPPVQQQLNLSTSGPSS 621

  Fly   512 TGVGVGGGAG--------TTGSPQAAYGAAAHQVYHPTPTSPTHQLYTNAVLNAPSALSYSASGW 568
            ..|....|..        ||||......:|.||  .|..:.| :.|:.:.....||:|..
Zfish   622 FPVSQSSGLNAIPNPVHPTTGSFSFPSTSAIHQ--GPMQSVP-NTLHPSTAYTFPSSLPK----- 678

  Fly   569 HNGSGAEYGLYQNAAAAYYQPEYIPLEIGYATHPLEPVDVSKTLDDPQAAMYKPSDEQGSVITLE 633
            |.|.     |...|..:|..|..||    ...|||:.:.:..:...|.
Zfish   679 HTGP-----LPNPAPTSYPFPTPIP----PGPHPLQSLTLPSSCSIPN----------------- 717

  Fly   634 CASSSLKSSHDIKIESSSLEHAGERGTVGGGAAVVSVPTAVVNGAPAVAADTWT-PLTPPQS 694
              :|.::|:......:.|..|...:..........|.|....:.||.:.:.:.| |..||.|
Zfish   718 --TSQIQSTFPQSYHNPSFSHIPPQMANHSQITSQSFPPLQTSSAPQLLSQSSTHPQCPPPS 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
byn	NP_524031.2	TBOX	86..268	CDD:238106	85/194 (44%)
tbx6	NP_705952.2	TBOX	62..247	CDD:238106	84/188 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396		9/34 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	428..453		5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	466..551		16/92 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	563..626		12/62 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	664..695		9/40 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..776		10/55 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810