Protein Alignment SdhAL and sdhA

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_415251.1
• Gene: sdhA / 945402
• ECOCYCID: EG10931
• Length: 588
• Species: Escherichia coli
• Alignment Length: 616
• Identity: 286/616 - (46%)
• Similarity: 381/616 - (61%)
• Gaps: 44/616 - (7%)

  Fly    46 KFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYD 110
            :|||:|||||||||||...:::.|...|::||:||||||||:||||:..||.|..:|:|::|.||
E. coli     7 EFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYD 71

  Fly   111 TVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRAC 175
            ||||||::|||:||.|||:....|:.||:..|:||||..||:|||||||||:.::| |..|.|..
E. coli    72 TVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFG-GEQAARTA 135

  Fly   176 ACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLIMSQ-GACVGCLAWKLDDGTFHRFLAKNT 239
            |.||||||||:||||.|.||:..:  .|.:::.|||:.:| ||.|||.|..::.|....|.|:.|
E. coli   136 AAADRTGHALLHTLYQQNLKNHTT--IFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARAT 198

  Fly   240 VVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGF 304
            |:|.||.||:|.|||..|..||||.....|..:|:.|||..|||||||.|||.|:|||.|||||:
E. coli   199 VLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGY 263

  Fly   305 FLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGNGC-GPLKDHVHLQLHHIDAKIIKQRLP 368
            .||..||||||||||.|||||.||||||::.:|:..|.|| ||...|..|:|.|:..::::.|||
E. coli   264 LLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLP 328

  Fly   369 GIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCAS 433
            ||:..:|.||.||..|||:||:||.||.||||||...|:.:|::|.|::.||.||::.||.:|.|
E. coli   329 GILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVS 393

  Fly   434 VHGANRLGANSLLDLIIFGRVCALDIAANNCPGDKPPQVEDKATEKSLDNFKRL-RCADGCIPTA 497
            ||||||||.||||||::|||...|.:..:...........:...|.|||...|. ...:|..|.|
E. coli   394 VHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVA 458

  Fly   498 VLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLAN 562
            : |..||..|..:.:|||||..:.:||.::..:.|:.|:.:..|.:..:|:..||.|||.|::..
E. coli   459 I-RKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMET 522

  Fly   563 AVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASI 627
            |.....:...|.||||:|:|.||..|.|                 |:|..|::
E. coli   523 AYATAVSANFRTESRGAHSRFDFPDRDD-----------------ENWLCHSL------------ 558

  Fly   628 KYRPVVDTTLDSSV-------APIPPAPRTY 651
             |.|..::....||       ...||..|||
E. coli   559 -YLPESESMTRRSVNMEPKLRPAFPPKIRTY 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	284/614 (46%)
sdhA	NP_415251.1	FAD_binding_2	27..588	CDD:481218	270/594 (45%)