Protein Alignment SdhAL and OSM1

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_012585.1
• Gene: OSM1 / 853510
• SGDID: S000003812
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 521
• Identity: 125/521 - (23%)
• Similarity: 211/521 - (40%)
• Gaps: 137/521 - (26%)

  Fly    32 RDASCKDEYSLIDHKFDAIVIGAGGAGMRAGFGLAEK-GFQTAIISKLFPTRSHTVAAQGGVNAA 95
            |..|..|:.|:   |...:|||:|.||:.....|..| .....::.|......:::.|..|:|.|
Yeast    23 RTLSGTDQTSM---KQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGA 84

  Fly    96 LSNMDK-----DDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAV--------CELDM------Y 141
            .::..:     |..:....||:..:...|..:.:..:.:|::.|:        .:||:      :
Yeast    85 HTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLDLLAQLGGH 149

  Fly   142 GMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDY 206
            .:|.:.:..||:   |.|.:.:                   .||...|...:.|.|:.....::.
Yeast   150 SVPRTHRSSGKL---PPGFEIV-------------------QALSKKLKDISSKDSNLVQIMLNS 192

  Fly   207 FVLDL-IMSQGACVGCLAWKLDDGTFHRFLAKNTVV-AAGGCG------------RVYFSTTAGH 257
            .|:|: :.:||...|.:  .:|:....:.:..:.|| .:||.|            .::..||.|.
Yeast   193 EVVDIELDNQGHVTGVV--YMDENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGK 255

  Fly   258 TCTGDGNAWVSRQELPLMDMEFVQFHPTGIYGAG-------CLITEGVRGEGGFFLN-CKGERFM 314
            ..||||...:|:....|:||:.||.||||.....       .|..|.:||.||..|: ..|.||
Yeast   256 QTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRF- 319

  Fly   315 ERYAPKAKDLASRDVVARAMTMEVLAGNGCGPLKDHVHLQL--------------HHIDAKIIKQ 365
                  ..:|::||.|    |||:  .:.| |..|:..|.:              .::...:||:
Yeast   320 ------TNELSTRDTV----TMEI--QSKC-PKNDNRALLVMSDKVYENYTNNINFYMSKNLIKK 371

  Fly   366 -------RLPGIMVTA-------------------------RIFAKVDVTKEPV----PVLPTVH 394
                   |...:..||                         ..|.| |::.|..    .|.|.||
Yeast   372 VSINDLIRQYDLQTTASELVTELKSYSDVNTKDTFDRPLIINAFDK-DISTESTVYVGEVTPVVH 435

  Fly   395 YNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALDI 459
            :.|||:..:.|.:|  |.:|.:..:..|:::.||.| ..||||||||.:|||:.::||:..|.:|
Yeast   436 FTMGGVKINEKSQV--IKKNSESVLSNGIFAAGEVS-GGVHGANRLGGSSLLECVVFGKTAADNI 497

  Fly   460 A 460
            |
Yeast   498 A 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	123/516 (24%)
OSM1	NP_012585.1	flavo_cyto_c	36..495	CDD:273816	117/500 (23%)