Protein Alignment SdhAL and SDH9

DIOPT Version :9

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_012490.1
• Gene: SDH9 / 853405
• SGDID: S000003581
• Length: 634
• Species: Saccharomyces cerevisiae
• Alignment Length: 655
• Identity: 367/655 - (56%)
• Similarity: 467/655 - (71%)
• Gaps: 29/655 - (4%)

  Fly     4 LFLKRAGQHVTRSLL----GPNGSRLLQVSCVRDASCKD-EYSLIDHKFDAIVIGAGGAGMRAGF 63
            |.||:.   :|:|.:    ..:.|.:.|:..|:..|... :|.:|||::|.:|:||||||:||.|
Yeast     2 LSLKKG---ITKSYILQRTFTSSSVVRQIGEVKSESKPPAKYHIIDHEYDCVVVGAGGAGLRAAF 63

  Fly    64 GLAEKGFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMC 128
            ||||.|::||.:||||||||||||||||:||||.||..||||.|.|||||||||||||:|||||.
Yeast    64 GLAEAGYKTACLSKLFPTRSHTVAAQGGINAALGNMHPDDWKSHMYDTVKGSDWLGDQDAIHYMT 128

  Fly   129 REAERAVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQT 193
            |||.::|.||:.|||||||..||:||||.||||:.|:||||.|.|.||.|||||||::||||||.
Yeast   129 REAPKSVIELEHYGMPFSRTEDGRIYQRAFGGQSKDFGKGGQAYRTCAVADRTGHAMLHTLYGQA 193

  Fly   194 LKHSDSCHYFVDYFVLDLIMSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHT 258
            ||  ::.|:|::||.:||:...|..||.:|:..:|||.|||.|..||:|.||.||.|||.|:.||
Yeast   194 LK--NNTHFFIEYFAMDLLTHNGEVVGVIAYNQEDGTIHRFRAHKTVIATGGYGRAYFSCTSAHT 256

  Fly   259 CTGDGNAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKD 323
            |||||||.|||...||.|:|||||||:||||:|||||||.||||||.||.:||||||||||.|||
Yeast   257 CTGDGNAMVSRAGFPLEDLEFVQFHPSGIYGSGCLITEGARGEGGFLLNSEGERFMERYAPTAKD 321

  Fly   324 LASRDVVARAMTMEVLAGNGCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVP 388
            |||||||:||:|||:.||.|.|..|||:.|||.|:..:::|:|||||..||.:||.||||:||:|
Yeast   322 LASRDVVSRAITMEIRAGRGVGKNKDHILLQLSHLPPEVLKERLPGISETAAVFAGVDVTQEPIP 386

  Fly   389 VLPTVHYNMGGIPTDYKGRVVTID-ENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFG 452
            ||||||||||||||.:.|..:||| |.|:::|:.||.:|||.:|.||||||||||||||||::||
Yeast   387 VLPTVHYNMGGIPTKWTGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSLLDLVVFG 451

  Fly   453 RVCALDIAANNCPGDKPPQVEDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREG 517
            |..|..||....||.....:......:|:.|..::|.|.|.:.|:.:|:.:||||.|..:|||..
Yeast   452 RAVANTIADTLQPGLPHKPLASNIGHESIANLDKVRNARGSLKTSQIRLNMQRTMQKDVSVFRTQ 516

  Fly   518 KLLKEGLLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAR 582
            ..|.||:..:.|:.:.|:|:..:|::|:|||:|||||||||:|..|.....:...||||||:|||
Yeast   517 DTLDEGVRNITEVDKTFEDVHVSDKSMIWNSDLVETLELQNLLTCATQTAVSASKRKESRGAHAR 581

  Fly   583 EDFKTRVDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTLD-SSVAPIPP 646
            ||:..|.|                 .:|||||:::..|......||||.|:..||| :..||:||
Yeast   582 EDYAKRDD-----------------VNWRKHTLSWQKGTSTPVKIKYRNVIAHTLDENECAPVPP 629

  Fly   647 APRTY 651
            |.|:|
Yeast   630 AVRSY 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	357/616 (58%)
		NADB_Rossmann	68..459	CDD:304358	264/391 (68%)
		Succ_DH_flav_C	502..651	CDD:280980	63/149 (42%)
SDH9	NP_012490.1	PTZ00139	5..634	CDD:240286	364/650 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344479
Domainoid	1	1.000	146	1.000	Domainoid score	I971
eggNOG	1	0.900	-	-		E1_COG1053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.957091	Normalized mean entropy	S148
OMA	1	1.010	-	-		QHG60640
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	O	PTHR11632
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1604
TreeFam	1	0.960	-	-
	11	10.660