Protein Alignment SdhAL and Sdha

DIOPT Version :9

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_075770.1
• Gene: Sdha / 66945
• MGIID: 1914195
• Length: 664
• Species: Mus musculus
• Alignment Length: 635
• Identity: 394/635 - (62%)
• Similarity: 492/635 - (77%)
• Gaps: 8/635 - (1%)

  Fly    18 LGPNGSRLLQVSCVRDASCKDEYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTR 82
            :|.|.....:||   || ...:|.::||:|||:|:||||||:||.|||:|.||.||.::||||||
Mouse    37 VGENKKASAKVS---DA-ISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTR 97

  Fly    83 SHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSR 147
            |||||||||:||||.||::|:|::|||||||||||||||:|||||..:|..:|.||:.|||||||
Mouse    98 SHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSR 162

  Fly   148 KPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLI 212
            ..|||||||.||||:|.:||||.|.|.|..||||||:|:|||||::|::..|  |||:||.|||:
Mouse   163 TEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTS--YFVEYFALDLL 225

  Fly   213 MSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDM 277
            |..|.|.|.:|..::||:.||..|||||:|.||.||.|||.|:.||.||||.|.|:|..||..|:
Mouse   226 MENGECRGVIALCIEDGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDL 290

  Fly   278 EFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGN 342
            ||||||||||||||||||||.|||||..:|.:||||||||||.||||||||||:|:||:|:..|.
Mouse   291 EFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGR 355

  Fly   343 GCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGR 407
            ||||.||||:|||||:..:.:..|||||..||.|||.|||||||:|||||||||||||||:|||:
Mouse   356 GCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ 420

  Fly   408 VVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALDIAANNCPGDKPPQV 472
            |:. ..||::|:|.|||:|||.:||||||||||||||||||::|||.|||.||.:..||||.|.:
Mouse   421 VLK-HVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSI 484

  Fly   473 EDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDI 537
            :..|.|:|:.|..:||.|||.|.|:.||:.:|::|..||||||.|.:|:||..|:::|....|.:
Mouse   485 KANAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKISQLYGDLKHL 549

  Fly   538 KTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQK 602
            ||.||.||||::|||||||||::..|:..|...|.||||||:|||||:|.||||.||..|:.||:
Mouse   550 KTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRVDEYDYSKPIQGQQ 614

  Fly   603 KKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTL-DSSVAPIPPAPRTY 651
            ||||.|||||||:::.....|..:::||||:|.|| ::..|.:|||.|:|
Mouse   615 KKPFGEHWRKHTLSYVDIKTGKVTLEYRPVIDKTLNEADCATVPPAIRSY 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	387/614 (63%)
		NADB_Rossmann	68..459	CDD:304358	268/390 (69%)
		Succ_DH_flav_C	502..651	CDD:280980	80/149 (54%)
Sdha	NP_075770.1	PTZ00139	35..664	CDD:240286	393/633 (62%)
		NADB_Rossmann	85..518	CDD:304358	288/435 (66%)
		Succ_DH_flav_C	513..664	CDD:280980	80/150 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.957091	Normalized mean entropy	S148
OMA	1	1.010	-	-		QHG60640
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	O	PTHR11632
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.730