Protein Alignment SdhAL and Sdha

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_075770.1
• Gene: Sdha / 66945
• MGIID: 1914195
• Length: 664
• Species: Mus musculus
• Alignment Length: 635
• Identity: 394/635 - (62%)
• Similarity: 492/635 - (77%)
• Gaps: 8/635 - (1%)

  Fly    18 LGPNGSRLLQVSCVRDASCKDEYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTR 82
            :|.|.....:||   || ...:|.::||:|||:|:||||||:||.|||:|.||.||.::||||||
Mouse    37 VGENKKASAKVS---DA-ISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTR 97

  Fly    83 SHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSR 147
            |||||||||:||||.||::|:|::|||||||||||||||:|||||..:|..:|.||:.|||||||
Mouse    98 SHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSR 162

  Fly   148 KPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLI 212
            ..|||||||.||||:|.:||||.|.|.|..||||||:|:|||||::|::..|  |||:||.|||:
Mouse   163 TEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTS--YFVEYFALDLL 225

  Fly   213 MSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDM 277
            |..|.|.|.:|..::||:.||..|||||:|.||.||.|||.|:.||.||||.|.|:|..||..|:
Mouse   226 MENGECRGVIALCIEDGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDL 290

  Fly   278 EFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGN 342
            ||||||||||||||||||||.|||||..:|.:||||||||||.||||||||||:|:||:|:..|.
Mouse   291 EFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGR 355

  Fly   343 GCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGR 407
            ||||.||||:|||||:..:.:..|||||..||.|||.|||||||:|||||||||||||||:|||:
Mouse   356 GCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ 420

  Fly   408 VVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALDIAANNCPGDKPPQV 472
            |:. ..||::|:|.|||:|||.:||||||||||||||||||::|||.|||.||.:..||||.|.:
Mouse   421 VLK-HVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSI 484

  Fly   473 EDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDI 537
            :..|.|:|:.|..:||.|||.|.|:.||:.:|::|..||||||.|.:|:||..|:::|....|.:
Mouse   485 KANAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKISQLYGDLKHL 549

  Fly   538 KTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQK 602
            ||.||.||||::|||||||||::..|:..|...|.||||||:|||||:|.||||.||..|:.||:
Mouse   550 KTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRVDEYDYSKPIQGQQ 614

  Fly   603 KKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTL-DSSVAPIPPAPRTY 651
            ||||.|||||||:::.....|..:::||||:|.|| ::..|.:|||.|:|
Mouse   615 KKPFGEHWRKHTLSYVDIKTGKVTLEYRPVIDKTLNEADCATVPPAIRSY 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	387/614 (63%)
Sdha	NP_075770.1	PTZ00139	35..664	CDD:240286	393/633 (62%)