Protein Alignment SdhAL and sdha

DIOPT Version :9

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001015989.1
• Gene: sdha / 548743
• XenbaseID: XB-GENE-956942
• Length: 665
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 389/626 - (62%)
• Similarity: 482/626 - (76%)
• Gaps: 10/626 - (1%)

  Fly    32 RDASCK------DEYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTRSHTVAAQG 90
            :|.|.|      .:|.::||.|||:|:||||||:||.|||:|.||.||.|:||||||||||||||
 Frog    44 KDTSAKLSDSISTQYPVVDHDFDAVVVGAGGAGLRAAFGLSEAGFNTACITKLFPTRSHTVAAQG 108

  Fly    91 GVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSRKPDGKIYQ 155
            |:||||.||:.|||::|||||||||||||||:|||||..:|..:|.||:.|||||||...|||||
 Frog   109 GINAALGNMEDDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVIELENYGMPFSRTEQGKIYQ 173

  Fly   156 RPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLIMSQGACVG 220
            |.||||:|.:||||.|.|.|..||||||:|:|||||::|::..|  |||:||.|||:|..|.|.|
 Frog   174 RAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTS--YFVEYFALDLLMENGECRG 236

  Fly   221 CLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDMEFVQFHPT 285
            .:|..::||:.|||.|||||:|.||.||.:||.|:.|||||||.|.|:|..||..|:||||||||
 Frog   237 VIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTCTGDGTAMVTRAGLPCQDLEFVQFHPT 301

  Fly   286 GIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGNGCGPLKDH 350
            ||||||||||||.|||||..:|.:||||||||||.||||||||||:|:||:|:..|.|||..|||
 Frog   302 GIYGAGCLITEGCRGEGGILINSEGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGKDKDH 366

  Fly   351 VHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGRVVTIDENG 415
            |:|||||:....:..|||||..||.|||.|||||||:|||||||||||||||:|||:|:| ..||
 Frog   367 VYLQLHHLPPSQLASRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVIT-HVNG 430

  Fly   416 KEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALDIAANNCPGDKPPQVEDKATEKS 480
            :::||.|||:|||.:.|||||||||||||||||::|||.|||.||.:..||:..|.:::.|.|:|
 Frog   431 EDRVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALSIAESCKPGEPVPSIKENAGEES 495

  Fly   481 LDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDIKTTDRTMV 545
            :.|..:||..:|...|:.||:.:|:||..||||||.|.:||||..|::.:.....||||.||.:|
 Frog   496 VANLDKLRFTNGSTRTSELRINMQKTMQNHAAVFRTGSVLKEGCEKLSAINSTMDDIKTFDRGIV 560

  Fly   546 WNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQKKKPFEEHW 610
            ||::|||||||||::..|:..|...|.||||||:|||||:|.|:||.||..|:.||:||.|.|||
 Frog   561 WNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKSFSEHW 625

  Fly   611 RKHTMTFALGNKGCASIKYRPVVDTTLDSSVAPIPPAPRTY 651
            ||||:::..| ||..|::||||:||||:.....:|||.|:|
 Frog   626 RKHTLSYVDG-KGKVSLEYRPVIDTTLNEDCVSVPPAIRSY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	386/619 (62%)
		NADB_Rossmann	68..459	CDD:304358	269/390 (69%)
		Succ_DH_flav_C	502..651	CDD:280980	82/148 (55%)
sdha	NP_001015989.1	PTZ00139	46..665	CDD:240286	387/622 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60640
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11632
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030