Protein Alignment SdhAL and sdha

DIOPT Version :9

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_957204.1
• Gene: sdha / 393884
• ZFINID: ZDB-GENE-040426-874
• Length: 661
• Species: Danio rerio
• Alignment Length: 649
• Identity: 396/649 - (61%)
• Similarity: 496/649 - (76%)
• Gaps: 18/649 - (2%)

  Fly     8 RAGQHVTRSLLGPNGSRLLQVSCVRDASCKD----EYSLIDHKFDAIVIGAGGAGMRAGFGLAEK 68
            :|.:.:..|:.|..|          ||...|    :|.::||:|||:|:||||||:||.|||:|.
Zfish    26 QANRQLHFSIYGKRG----------DAKISDGVSNQYPVVDHEFDAVVVGAGGAGLRAAFGLSEA 80

  Fly    69 GFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAER 133
            ||.||.::|||||||||||||||:||||.||::|||::|||||||||||||||:|||||..:|..
Zfish    81 GFNTACVTKLFPTRSHTVAAQGGINAALGNMEQDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPA 145

  Fly   134 AVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSD 198
            ||.||:.:||||||..|||||||.||||:|.:||||.|.|.|..||||||:|:|||||::|::..
Zfish   146 AVVELENFGMPFSRTDDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDT 210

  Fly   199 SCHYFVDYFVLDLIMSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDG 263
            |  |||:||.|||:|..|.|.|.:|..::||:.|||.|||||:|.||.||.:||.|:.||.||||
Zfish   211 S--YFVEYFALDLLMEDGECKGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTSTGDG 273

  Fly   264 NAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRD 328
            ||.|:|..||..|:||||||||||||||||||||.|||||..:|.:||||||||||.||||||||
Zfish   274 NAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPNAKDLASRD 338

  Fly   329 VVARAMTMEVLAGNGCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTV 393
            ||:|:||:|:..|.|.||.||||||||||:..:.:..|||||..||.|||.|||||||:||||||
Zfish   339 VVSRSMTIEIREGRGVGPDKDHVHLQLHHLPPQQLAARLPGISETAMIFAGVDVTKEPIPVLPTV 403

  Fly   394 HYNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALD 458
            |||||||||:|||:|:|. ::|::.||.|||:|||..||||||||||||||||||::|||.|||.
Zfish   404 HYNMGGIPTNYKGQVITY-KDGQDHVVPGLYACGEAGCASVHGANRLGANSLLDLVVFGRACALT 467

  Fly   459 IAANNCPGDKPPQVEDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEG 523
            ||..:.||:|...::..|.|.|:.|..::|.|:|...|:.:|:.:|:||..||||||.|.:||||
Zfish   468 IAEIDTPGEKLSPLKPNAGEASVANLDKMRYANGSTRTSEIRLNMQKTMQSHAAVFRTGDVLKEG 532

  Fly   524 LLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTR 588
            .:|:..:.:...:|||.||.:|||::|||||||||::.|||..|.:.|.||||||:|||||||.|
Zfish   533 CVKMESVYKSMDNIKTFDRGIVWNTDLVETLELQNLMLNAVQTIVSAEARKESRGAHAREDFKDR 597

  Fly   589 VDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTLDS-SVAPIPPAPRTY 651
            |||.||..||.||.|||||:||||||:::.....|..:::||||:|::||: ..|.||||.|:|
Zfish   598 VDEYDYSKPLQGQVKKPFEQHWRKHTLSYVDPETGKVTLEYRPVIDSSLDAEDCAAIPPAIRSY 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	389/618 (63%)
		NADB_Rossmann	68..459	CDD:304358	270/390 (69%)
		Succ_DH_flav_C	502..651	CDD:280980	85/149 (57%)
sdha	NP_957204.1	PTZ00139	45..661	CDD:240286	389/618 (63%)
		NADB_Rossmann	82..468	CDD:304358	269/388 (69%)
		Succ_DH_flav_C	510..661	CDD:280980	85/150 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60640
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	O	PTHR11632
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.790