Protein Alignment SdhAL and sdh1

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_594319.1
• Gene: sdh1 / 2541690
• PomBaseID: SPAC1556.02C
• Length: 641
• Species: Schizosaccharomyces pombe
• Alignment Length: 635
• Identity: 373/635 - (58%)
• Similarity: 464/635 - (73%)
• Gaps: 36/635 - (5%)

  Fly    24 RLLQVSCVRDASCKDEYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTRSHTVAA 88
            |..|||    .|...:|.:|||.:||||:||||||:||.|||||.||.||.|:||||||||||||
pombe    36 RAKQVS----TSESVKYPVIDHTYDAIVVGAGGAGLRATFGLAEAGFNTACITKLFPTRSHTVAA 96

  Fly    89 QGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSRKPDGKI 153
            |||:||||.||.||||::|||||||||||||||:|||||.:||.:||.||:.:|:||||..:|||
pombe    97 QGGINAALGNMTKDDWRWHFYDTVKGSDWLGDQDAIHYMTKEAPKAVLELEHFGVPFSRTKEGKI 161

  Fly   154 YQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLIMSQGAC 218
            |||.||||:|:|||||.|.|..|.||||||:::||||||:|||  :.::|::||.:||||..|.|
pombe   162 YQRAFGGQSLEYGKGGQAYRCAAVADRTGHSILHTLYGQSLKH--NTNFFIEYFAMDLIMEGGEC 224

  Fly   219 VGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDMEFVQFH 283
            .|.:|..|:||:.|||.|..|::|.||.||.|||.|:.|||||||||.|||..|||.|:||||||
pombe   225 RGVIAMNLEDGSIHRFRAHKTILATGGYGRAYFSCTSAHTCTGDGNAMVSRAGLPLQDLEFVQFH 289

  Fly   284 PTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGNGCGPLK 348
            ||||||||||||||.|||||:.||.|||||||||||.||||||||||:||||:|:..|.|.||.|
pombe   290 PTGIYGAGCLITEGCRGEGGYLLNSKGERFMERYAPTAKDLASRDVVSRAMTVEIREGRGVGPEK 354

  Fly   349 DHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGRVVTIDE 413
            ||.:|||.|:.|:|:|:|||||..||.|||.|||||||:|||||||||||||||.:.|.|:||||
pombe   355 DHCYLQLSHLPAEILKERLPGISETAAIFAGVDVTKEPIPVLPTVHYNMGGIPTRFTGEVLTIDE 419

  Fly   414 NGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCAL---DIAANNCPGDKPPQVEDK 475
            |||:::|.|||:.||.:|.||||.||||||||||:::|||.|||   |....|.| .||     .
pombe   420 NGKDKIVPGLYAAGEAACVSVHGGNRLGANSLLDIVVFGRACALHIKDTLEPNTP-HKP-----L 478

  Fly   476 ATEKSLDNFK---RLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDI 537
            |.:..||:.|   ::|.:.|...|:.:|:::|:||.:..:|||..:.|:||:..:|.:...:|||
pombe   479 AADAGLDSLKFLDQIRTSQGPKHTSEIRLDMQKTMQRDVSVFRMEETLQEGVKNIARVDGTYKDI 543

  Fly   538 KTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQK 602
            ...||.::||::|||.|||:|:|..||....|..|||||||:|||||:..|.|
pombe   544 GIRDRGLIWNTDLVEALELRNLLTCAVQTANAALNRKESRGAHAREDYPERDD------------ 596

  Fly   603 KKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTLD-SSVAPIPPAPRTY 651
                 ::|.|||:|:........::|||.|..||:| :.|.|:||..|.|
pombe   597 -----KNWIKHTLTWQHKTGDPVTLKYRAVTRTTMDENEVKPVPPFKRVY 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	367/620 (59%)
sdh1	NP_594319.1	PTZ00139	29..641	CDD:240286	372/633 (59%)