Protein Alignment SdhAL and sdha-1

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_509446.1
• Gene: sdha-1 / 181108
• WormBaseID: WBGene00015391
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 387/649 - (59%)
• Similarity: 486/649 - (74%)
• Gaps: 10/649 - (1%)

  Fly     8 RAGQHVTRSLLGPNGSRLLQVSCVR--DASCKD--EYSLIDHKFDAIVIGAGGAGMRAGFGLAEK 68
            ||..:..|:.:   .:|.:.:|...  ||...|  :|.::||.:||:|:||||||:||..||||.
 Worm     3 RAASNGLRNTV---AARSVSLSAANHSDAKRSDIAQYKVVDHAYDAVVVGAGGAGLRAAMGLAEG 64

  Fly    69 GFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQNAIHYMCREAER 133
            |.:||:|:|||||||||||||||:||||.||:.|:|::|||||||||||||||:|||||.|||||
 Worm    65 GLKTAVITKLFPTRSHTVAAQGGINAALGNMNPDNWRWHFYDTVKGSDWLGDQDAIHYMTREAER 129

  Fly   134 AVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIHTLYGQTLKHSD 198
            ||.||:.|||||||..|||||||.||||:.|:|:||.|.|.|..||||||:|:|||||.:|::
 Worm   130 AVIELENYGMPFSRTTDGKIYQRAFGGQSNDFGRGGQAHRTCCVADRTGHSLLHTLYGASLQY-- 192

  Fly   199 SCHYFVDYFVLDLIMSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFSTTAGHTCTGDG 263
            :|:|||:||.|||||..|.|||.:|..|:|||.|||.:||||:|.||.||.:||.|:.|||||||
 Worm   193 NCNYFVEYFALDLIMENGVCVGVIAMDLEDGTIHRFRSKNTVLATGGYGRAFFSCTSAHTCTGDG 257

  Fly   264 NAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERYAPKAKDLASRD 328
            .|..:|..:...||||||||||||||||||||||.|||||:.:|..||||||||||.||||||||
 Worm   258 TALTARAGINNSDMEFVQFHPTGIYGAGCLITEGSRGEGGYLVNSAGERFMERYAPNAKDLASRD 322

  Fly   329 VVARAMTMEVLAGNGCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDVTKEPVPVLPTV 393
            ||:|:||:|::.|.|.||.|||::|||||:.|:.::||||||..||.|||.|||||||:||:|||
 Worm   323 VVSRSMTVEIMEGRGVGPDKDHIYLQLHHLPAEQLQQRLPGISETAMIFAGVDVTKEPIPVIPTV 387

  Fly   394 HYNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLDLIIFGRVCALD 458
            ||||||:||:|||:|:.......::||.|||:.||....||||||||||||||||:||||.||:|
 Worm   388 HYNMGGVPTNYKGQVLNYTPKKGDEVVPGLYAAGECGAHSVHGANRLGANSLLDLVIFGRACAID 452

  Fly   459 IAANNCPGDKPPQVEDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAAVFREGKLLKEG 523
            |..|...|...|::...|.|.|:.|..:||...|.|.||.||:.:|::|..||||||.|.:||||
 Worm   453 ILKNTSAGVGVPELPKNAGEASVANIDKLRHNKGDISTAELRLTMQKSMQNHAAVFRRGDILKEG 517

  Fly   524 LLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESRGSHAREDFKTR 588
            :..:::|.:....:...|:.:||||:|:|||||||:|.||...|.|.|||:||||:|||:||..|
 Worm   518 VKVLSKLYKDQAHLNVADKGLVWNSDLIETLELQNLLINATQTIVAAENREESRGAHARDDFPDR 582

  Fly   589 VDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTLDSSVAP-IPPAPRTY 651
            :|||||..||.||.||..::|||||::..:....|..|:.||||:|||||.|... :||..|:|
 Worm   583 LDELDYSKPLEGQTKKELKDHWRKHSIIRSNIETGEVSLDYRPVIDTTLDKSETDWVPPKVRSY 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	379/616 (62%)
sdha-1	NP_509446.1	FAD_binding_2	36..646	CDD:481218	378/611 (62%)