Protein Alignment SdhAL and Sdha

DIOPT Version :9

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_569112.1
• Gene: Sdha / 157074
• RGDID: 621557
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 660
• Identity: 395/660 - (59%)
• Similarity: 494/660 - (74%)
• Gaps: 22/660 - (3%)

  Fly     9 AGQHVTRSLLGPNGSRLLQVSCVR----------DASCK------DEYSLIDHKFDAIVIGAGGA 57
            ||......||  .|.||......|          .||.|      .:|.::||:|||:|:|||||
  Rat     2 AGVGAVSRLL--RGRRLALAGATRGFHFSVGESKKASAKVSDAISTQYPVVDHEFDAVVVGAGGA 64

  Fly    58 GMRAGFGLAEKGFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDDWKYHFYDTVKGSDWLGDQN 122
            |:||.|||:|.||.||.::|||||||||||||||:||||.||::|:|::|||||||||||||||:
  Rat    65 GLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQD 129

  Fly   123 AIHYMCREAERAVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKGGVARRACACADRTGHALIH 187
            |||||..:|..:|.||:.|||||||..||:||||.||||:|.:||||.|.|.|..||||||:|:|
  Rat   130 AIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLH 194

  Fly   188 TLYGQTLKHSDSCHYFVDYFVLDLIMSQGACVGCLAWKLDDGTFHRFLAKNTVVAAGGCGRVYFS 252
            ||||::|::..|  |||:||.|||:|..|.|.|.:|..::||:.||..||||::|.||.||.|||
  Rat   195 TLYGRSLRYDTS--YFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTIIATGGYGRTYFS 257

  Fly   253 TTAGHTCTGDGNAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGVRGEGGFFLNCKGERFMERY 317
            .|:.||.||||.|.|:|..||..|:||||||||||||||||||||.|||||..:|.:||||||||
  Rat   258 CTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERY 322

  Fly   318 APKAKDLASRDVVARAMTMEVLAGNGCGPLKDHVHLQLHHIDAKIIKQRLPGIMVTARIFAKVDV 382
            ||.||||||||||:|:||:|:..|.||||.||||:|||||:..:.:..|||||..||.|||.|||
  Rat   323 APVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDV 387

  Fly   383 TKEPVPVLPTVHYNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGETSCASVHGANRLGANSLLD 447
            ||||:|||||||||||||||:|||:|:. ..||::|:|.|||:|||.:|||||||||||||||||
  Rat   388 TKEPIPVLPTVHYNMGGIPTNYKGQVLK-HVNGQDQIVPGLYACGEAACASVHGANRLGANSLLD 451

  Fly   448 LIIFGRVCALDIAANNCPGDKPPQVEDKATEKSLDNFKRLRCADGCIPTAVLRMELQRTMTKHAA 512
            |::|||.|||.||.:..||||.|.::..|.|:|:.|..:||.|||.:.|:.||:.:|::|..|||
  Rat   452 LVVFGRACALSIAESCRPGDKVPPIKANAGEESVMNLDKLRFADGSVRTSELRLSMQKSMQSHAA 516

  Fly   513 VFREGKLLKEGLLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQNMLANAVHIITAMENRKESR 577
            |||.|.:|:||..||::|....:.:||.||.||||::|||||||||::..|:..|...|.|||||
  Rat   517 VFRVGSVLQEGCEKVSQLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESR 581

  Fly   578 GSHAREDFKTRVDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKGCASIKYRPVVDTTL-DSSV 641
            |:|||||:|.|:||.||..|:.||:||||.|||||||:::.....|..::.||||:|.|| ::..
  Rat   582 GAHAREDYKVRIDEYDYSKPIEGQQKKPFAEHWRKHTLSYVDTKTGKVTLDYRPVIDKTLNEADC 646

  Fly   642 APIPPAPRTY 651
            |.:|||.|:|
  Rat   647 ATVPPAIRSY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	PTZ00139	37..651	CDD:240286	384/620 (62%)
		NADB_Rossmann	68..459	CDD:304358	266/390 (68%)
		Succ_DH_flav_C	502..651	CDD:280980	79/149 (53%)
Sdha	NP_569112.1	PTZ00139	44..656	CDD:240286	383/614 (62%)
		NADB_Rossmann	77..463	CDD:304358	265/388 (68%)
		Succ_DH_flav_C	507..656	CDD:280980	79/148 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60640
OrthoDB	1	1.010	-	-		D171709at33208
OrthoFinder	1	1.000	-	-		FOG0002411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100447
Panther	1	1.100	-	-	O	PTHR11632
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1604
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830