Protein Alignment SdhAL and SdhA

DIOPT Version :10

• Sequence 1: NP_648523.1
• Gene: SdhAL / 39348
• FlyBaseID: FBgn0036222
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_311518.5
• Gene: SdhA / 1272618
• VectorBaseID: AGAMI1_012103
• Length: 659
• Species: Anopheles gambiae
• Alignment Length: 613
• Identity: 401/613 - (65%)
• Similarity: 491/613 - (80%)
• Gaps: 3/613 - (0%)

  Fly    39 EYSLIDHKFDAIVIGAGGAGMRAGFGLAEKGFQTAIISKLFPTRSHTVAAQGGVNAALSNMDKDD 103
            ||.::||.:||:|:||||||:||.|||..:||:||:|:|||||||||||||||:||||.||::||
Mosquito    50 EYPVVDHTYDAVVVGAGGAGLRAAFGLVAEGFKTAVITKLFPTRSHTVAAQGGINAALGNMEEDD 114

  Fly   104 WKYHFYDTVKGSDWLGDQNAIHYMCREAERAVCELDMYGMPFSRKPDGKIYQRPFGGQTLDYGKG 168
            ||:|.|||||||||||||:|||||.|||.:||.||:.|||||||.||||||||.||||:|.||||
Mosquito   115 WKWHMYDTVKGSDWLGDQDAIHYMTREAPKAVIELENYGMPFSRTPDGKIYQRAFGGQSLKYGKG 179

  Fly   169 GVARRACACADRTGHALIHTLYGQTLKHSDSCHYFVDYFVLDLIMSQGACVGCLAWKLDDGTFHR 233
            |.|.|.|..||||||:|:||||||:|.:  .|:||::||.:||:|..|.|||.:|..|:||:.||
Mosquito   180 GQAHRCCCVADRTGHSLLHTLYGQSLSY--DCNYFIEYFAMDLLMQNGECVGVIAMNLEDGSIHR 242

  Fly   234 FLAKNTVVAAGGCGRVYFSTTAGHTCTGDGNAWVSRQELPLMDMEFVQFHPTGIYGAGCLITEGV 298
            |.|||||:|.||.||.|||.|:.|||||||.|.|:|..||..|:||||||||||||||||||||.
Mosquito   243 FRAKNTVLATGGYGRAYFSCTSAHTCTGDGTAMVARAGLPSEDLEFVQFHPTGIYGAGCLITEGC 307

  Fly   299 RGEGGFFLNCKGERFMERYAPKAKDLASRDVVARAMTMEVLAGNGCGPLKDHVHLQLHHIDAKII 363
            |||||:.:|.:||||||||||.||||||||||:|:||:|:..|.||||.||||:|||||:..:.:
Mosquito   308 RGEGGYLINSQGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGPEKDHVYLQLHHLPPEQL 372

  Fly   364 KQRLPGIMVTARIFAKVDVTKEPVPVLPTVHYNMGGIPTDYKGRVVTIDENGKEQVVKGLYSCGE 428
            .||||||..||.|||.||||:||:||||||||||||:||:|||:|:| .|||.::||.|||:|||
Mosquito   373 AQRLPGISETAMIFAGVDVTREPIPVLPTVHYNMGGVPTNYKGQVLT-TENGADRVVPGLYACGE 436

  Fly   429 TSCASVHGANRLGANSLLDLIIFGRVCALDIAANNCPGDKPPQVEDKATEKSLDNFKRLRCADGC 493
            .:|:||||||||||||||||::|||.||..||..|.||:|...::..|.|.|:.|...:|.|||.
Mosquito   437 AACSSVHGANRLGANSLLDLVVFGRACAKTIAEENRPGEKVQDLKPNAGEASVANLDWVRNADGQ 501

  Fly   494 IPTAVLRMELQRTMTKHAAVFREGKLLKEGLLKVAELCEQFKDIKTTDRTMVWNSNLVETLELQN 558
            :||:.||:.:|:||..|||||||.|.|:||:.|:.::.:..||:|.:||::||||:|||||||||
Mosquito   502 VPTSTLRLNMQKTMQTHAAVFREEKTLQEGVRKMGDIYKTIKDVKVSDRSLVWNSDLVETLELQN 566

  Fly   559 MLANAVHIITAMENRKESRGSHAREDFKTRVDELDYGAPLAGQKKKPFEEHWRKHTMTFALGNKG 623
            :|.||...|.|.||||||||:|||||:|.||||.|:..||.||:|||.||||||||:|:.....|
Mosquito   567 LLLNANMTIVAAENRKESRGAHAREDYKQRVDEYDFSKPLEGQQKKPVEEHWRKHTLTWIDPATG 631

  Fly   624 CASIKYRPVVDTTLDSSVAPIPPAPRTY 651
            ..:|.||||:|.||....|.:|||.|:|
Mosquito   632 NVTIDYRPVIDETLSEECATVPPAIRSY 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdhAL	NP_648523.1	FAD_binding_2	37..651	CDD:481218	400/611 (65%)
SdhA	XP_311518.5	None