DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11588 and pdia6

DIOPT Version :9

Sequence 1:	NP_001261729.1	Gene:	CG11588 / 39347	FlyBaseID:	FBgn0036221	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_922915.2	Gene:	pdia6 / 322160	ZFINID:	ZDB-GENE-030131-879	Length:	440	Species:	Danio rerio

Alignment Length:	225	Identity:	51/225 - (22%)
Similarity:	71/225 - (31%)	Gaps:	77/225 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 RSSRKSESSYLMAEYGDGLITRIDEGNWKEV--LTGE------------WLLLICSSHQPSCG-- 80
            |...|:..|....:.|.|      .||.|:|  ||.:            ||:   ....|.||
Zfish   138 RLGGKTGGSDYSRQSGGG------AGNKKDVVELTDDNFDRTVLESDDVWLV---EFFAPWCGHC 193

  Fly    81 -----DWKAVLYQLASTSMGCLDVDLAFGDLSTNFWLRGRFS--AFREANVYHVVDGEFRRLSSS 138
                 :|.|...::...:.|  .|.||..|.:.:..|..||.  .|....|       ||:....
Zfish   194 KNLEPEWTAAATEVKEQTKG--KVRLAAEDATVHQGLASRFGIRGFPTIKV-------FRKGEEP 249

  Fly   139 HD-----TNSILNLLLLREWSELPPMPFWLHPTSTWSTSAEFVLKTAVDLKDLDILGRNAWKTAL 198
            .|     |.|.:....|..:|:..|.|           ..:.||...: ||          ||..
Zfish   250 EDYQGGRTRSDIVARALELYSDNIPAP-----------ELQEVLNEGI-LK----------KTCE 292

  Fly   199 ILDLIFFIVTPYIL---------WLTIMTT 219
            ...|....|.|:||         :|.:|.|
Zfish   293 DYQLCIIAVLPHILDTGASGRNSYLEVMKT 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11588	NP_001261729.1	Thioredoxin_like	51..148	CDD:294274	28/124 (23%)
pdia6	NP_922915.2	ER_PDI_fam	25..262	CDD:273457	33/141 (23%)
		PDI_a_P5	26..128	CDD:239299
		PDI_a_P5	161..266	CDD:239299	25/116 (22%)
		P5_C	275..404	CDD:239281	15/70 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910