DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11588 and Y49E10.4

DIOPT Version :9

Sequence 1:	NP_001261729.1	Gene:	CG11588 / 39347	FlyBaseID:	FBgn0036221	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_499613.1	Gene:	Y49E10.4 / 176664	WormBaseID:	WBGene00013030	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	44/201 - (21%)
Similarity:	69/201 - (34%)	Gaps:	79/201 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SYLMAEYGD-GLITRIDEGNWKEVLTGEWLLLICSSHQ-------PSCGDWKA--------VLYQ 88
            ||..::|.| |....:.||..|.|:.     .:|...|       ||..|.::        :|.:
Worm   257 SYAESKYDDFGAAPEVVEGTGKAVVE-----TVCKDKQLCIFTFLPSIFDCQSKCRKQKIDMLNE 316

  Fly    89 LAS----TSMGCL--------DVDLAF--GD---------------LSTNFWLRGRFS--AFRE- 121
            ||:    .|.|.:        :|..||  ||               .||..   |:||  ..:|
Worm   317 LATIFKKRSFGWVWMEGGAQENVQRAFEIGDYGFPVLIAMSPKKMMYSTQI---GQFSVDGIKEF 378

  Fly   122 ANVYHVVDGEFRRLSSSHDTNSILNLLLLREW----SELPPMPFWLHPTSTWSTSAEFVLKTAVD 182
            .|..:...|....:..:|.:|:.|.::..:.|    .|||.|                   ..:|
Worm   379 LNAVNYGKGRVLEIKPTHLSNNFLKIVETQPWDGKDKELPVM-------------------EDID 424

  Fly   183 LKDLDI 188
            |.|:|:
Worm   425 LSDVDM 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11588	NP_001261729.1	Thioredoxin_like	51..148	CDD:294274	30/143 (21%)
Y49E10.4	NP_499613.1	PDI_a_P5	26..127	CDD:239299
		PDI_a_P5	156..259	CDD:239299	1/1 (100%)
		P5_C	269..405	CDD:239281	30/143 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910