DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sprn and Ccdc181

DIOPT Version :9

Sequence 1:	NP_001163425.2	Gene:	Sprn / 39344	FlyBaseID:	FBgn0036218	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001014153.1	Gene:	Ccdc181 / 360867	RGDID:	1309708	Length:	509	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	59/299 - (19%)
Similarity:	113/299 - (37%)	Gaps:	88/299 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LDMACAGQ-EVEQVAEENVFET--GPQLKLPENQPINDSITTETNETKLPSTEALNVL------N 174
            :::||..: :::|..:|...||  ||||..|:..|.::::....:...:||.:.|:.:      |
  Rat    38 IEVACKKEDDLDQELKEKETETELGPQLSDPDKPPKDEALPRRNDFISVPSIQPLDPISDSDSEN 102

  Fly   175 LAEFSEPVMEK--SNISIEEVNLTGAEEI---------NEPISDEPNSQLVESAAKLQPKSLGIQ 228
            ..:.|:|..:|  .:...|||.....|:|         .||::|:...:|     |.:.|.:.::
  Rat   103 SFQDSKPENQKDLEDEEDEEVRRYIMEKIIEANKLLQTQEPVNDKRERKL-----KFKDKLVDLE 162

  Fly   229 IPPLQIEDLISPLVE-QPKIATKLGVISFLTGNKLALTPSVRLSFGDRVTTRTNKKSKEIVQQQA 292
            :|||:..|....|:| :..::.||..:..                           |.::.|:
  Rat   163 VPPLEDSDTCKVLLENETNMSGKLSQLCI---------------------------SGDLGQE-- 198

  Fly   293 SKALKALISVFTMQRRLEASQCDNSNN----SRSKRFEQLKSSLTFSRVFRQNIFQP-------- 345
                ..|:||..       ..|:.::.    .|..:||    .:....:..|....|
  Rat   199 ----SMLMSVTN-------GGCEENDRKILVERDGKFE----LMNLQDIESQGFLPPISSANGME 248

  Fly   346 --TSKIESRQQNTDANSLESGEPNFK----STSAYKEPL 378
              :|::..|..|.....::..||..|    :.|...|||
  Rat   249 HESSQLPLRSANLSVGGIKKEEPEAKIHIMTLSQAGEPL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sprn	NP_001163425.2	PH-like	446..562	CDD:302622
Ccdc181	NP_001014153.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..122		19/83 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	287..368		1/1 (100%)
		DUF5401	<337..>494	CDD:375164
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960