Protein Alignment CycA and CLB2

DIOPT Version :10

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_015444.1
• Gene: CLB2 / 856236
• SGDID: S000006323
• Length: 491
• Species: Saccharomyces cerevisiae
• Alignment Length: 472
• Identity: 122/472 - (25%)
• Similarity: 209/472 - (44%)
• Gaps: 88/472 - (18%)

  Fly    69 RDVRNLNVDENVEYGAKKSNV-VPVVEQFKT--------------FSVYEDNNDTQVAPSGKSLA 118
            |:|:.|.::.......:|||. .|.:..||:              |:....:..|......::|.
Yeast    21 RNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSRIPQFTRESVSRSTAAQEEKRTLK 85

  Fly   119 S----------LVDKENHD---VKFGA---------------------GQKELVDYDLDSTPMSV 149
            .          |.||||.|   .:|||                     ..||::.:|......|.
Yeast    86 ENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKGVGSS 150

  Fly   150 TDV------QSPMSVDRSILGVIQS-SDISVGTETGVSPTGRVKELPPR------NDRQRF---- 197
            |:|      ...:...||.|.|..: |:...|.:..:| |...:|||.:      |.::.:
Yeast   151 TEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPIS-TIVEQELPKKFKVCDENGKEEYEWED 214

  Fly   198 ---------LEVVQYQMDILEYFRESEKKHRPK--PLYMRRQKDISHNMRSILIDWLVEVSEEYK 251
                     ..|.:|..||.||..:.|....||  .||..|.   .|..|.||::|||::..::.
Yeast   215 LDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRN---IHQNRDILVNWLVKIHNKFG 276

  Fly   252 LDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQV 316
            |..|||||::..:||||.:..|...|||||||:.::||:||||:|.|.:..|...||.:.|:.::
Yeast   277 LLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEI 341

  Fly   317 LRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSS 381
            ...|:.|||.|.|:|..|....|:...:...|...:.:.:..::.|:||::.. ::..||||.::
Yeast   342 KEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFR-FIGILPSLCAA 405

  Fly   382 ASVALARHILGMEMWTPRLEEIT-TYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKV 445
            |::.::|.:||...|...|...: .|..|:| ..|.|:...:..:..::.:..| ||....:.|.
Yeast   406 AAMFMSRKMLGKGKWDGNLIHYSGGYTKEEL-APVCHMIMDYLVSPIVHDEFHR-KYQSRRFMKA 468

  Fly   446 AMME---SVEMSKDDFD 459
            :::.   ::::.|:.:|
Yeast   469 SIISVQWALKVRKNGYD 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	53/128 (41%)
		Cyclin_C	334..450	CDD:397230	25/119 (21%)
CLB2	NP_015444.1	COG5024	8..487	CDD:227357	122/472 (26%)