Protein Alignment CycA and CCNB3

DIOPT Version :9

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_016885402.1
• Gene: CCNB3 / 85417
• HGNCID: 18709
• Length: 1404
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 153/534 - (28%)
• Similarity: 242/534 - (45%)
• Gaps: 106/534 - (19%)

  Fly     8 QDMSNKENPGIKIPAGVKNT--KQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRD 70
            :.:..:|.|.||     |.|  |:|||:     :.:.:.....|..:...|..| ..||...|::
Human   894 ESLDLQEKPSIK-----KETLLKKPLAL-----KMSTINEAVLFEDMIALNEKP-TTGKELSFKE 947

  Fly    71 --------------------VRNLNVDENVEYGA-----KKSNVVPVVEQFKTFSV-----YEDN 105
                                |..:....||...|     .||::..:....|:.::     :||.
Human   948 PLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINEAFLFEDM 1012

  Fly   106 NDTQVAP-SGKSLA---SLVDKENHDVK-------FGAGQKELVDYDLDSTPMSVTD---VQSPM 156
            ......| :||.|:   .|..:|:...|       |...|.....|...:||.|:|:   :.:..
Human  1013 ITLNEKPTTGKELSFKEPLALQESPTCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATMT 1077

  Fly   157 SVDRSILGVIQSSDISVGTETGVSP--TGRVKE-LPPRNDRQR------FLEVVQYQMDILEYFR 212
            ||.:| ....:||.....::..|||  .|..|| :.||.|...      |..:  |..:|..|.:
Human  1078 SVGKS-RTTTESSACESASDKPVSPQAKGTPKEQITPREDIDEDSSDPSFNPM--YAKEIFSYMK 1139

  Fly   213 ESE-----KKHRPKPL--YMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQ 270
            |.|     :.|....|  ||.||.:|:.:||:||:||||||...:::..|||||:|..:|.:|.:
Human  1140 EREIEETAQSHEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMK 1204

  Fly   271 MAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPT 335
            ....:.||||:|..|..||||:||...|.|.:||::.||:|.:::||.||..||.:|..|:..|.
Human  1205 AVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPI 1269

  Fly   336 AYVFINTYAVLCDMPEKLKYMTL--YISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTP 398
            ||.|:..|| .| :...:|.:||  ||.|::|.|.. |:|...|.:::||:.||.::..:..|.|
Human  1270 AYHFLRRYA-RC-IHTNMKTLTLSRYICEMTLQEYH-YVQEKASKLAAASLLLALYMKKLGYWVP 1331

  Fly   399 RLEEITTYKLEDLKTVVLHLCHTHKTAKELN----------TQAMREKYNRDTYKKVAMMESVEM 453
            .||..:.|.:.:|          |...::||          .:|:..||:...:.:||.:.:::|
Human  1332 FLEHYSGYSISEL----------HPLVRQLNKLLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDM 1386

  Fly   454 SKDDFDQLCEAYNC 467
            .|     |.|..||
Human  1387 LK-----LEEILNC 1395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	56/132 (42%)
		Cyclin_C	334..450	CDD:281044	36/127 (28%)
CCNB3	XP_016885402.1	Cyclin_N	1133..1266	CDD:306612	56/132 (42%)
		Cyclin_C	1268..1384	CDD:308564	36/128 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D520533at33208
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820