Protein Alignment CycA and CLB4

DIOPT Version :9

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_013311.1
• Gene: CLB4 / 850907
• SGDID: S000004200
• Length: 460
• Species: Saccharomyces cerevisiae
• Alignment Length: 519
• Identity: 127/519 - (24%)
• Similarity: 230/519 - (44%)
• Gaps: 127/519 - (24%)

  Fly     1 MASFQIHQDMSNKENPGI---KIPAGVK--NTKQPLAVIGG----KAEK--NAL-----APRANF 49
            :...:|..:.:|:|...:   .:..|:|  ..:|....:|.    ||.|  ||:     ..:.||
Yeast    16 IGDIEIQDENANQEVKNVLYQGVQKGIKRLEKRQRRVALGDVTSQKANKIHNAIHNKFHQTKNNF 80

  Fly    50 AVLNGNNNVPRPAGKVQVFRDVRNLNV--------------DENVEYGA------KKSNVVPVVE 94
            .:    .|:...|...:..||||:.:.              ||.|...|      ::.|    .:
Yeast    81 EI----ENIRSSALVKEQQRDVRHEDSDYFLIDSSEGSSTDDEQVNEDAIDDLLSRRVN----DQ 137

  Fly    95 QFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDS-----TPMSVTDVQS 154
            |.:...||||                         |....:::::.|:||     :|::..::|:
Yeast   138 QIQADEVYED-------------------------FDGEMQDVIEEDVDSQIEPLSPINNDEIQT 177

  Fly   155 PMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHR 219
              .:||:.....:|           .|.      |..:|....:.||:|..||..|.||.|.|:|
Yeast   178 --ELDRAFEKYFRS-----------VPN------PLDDDTHDVVMVVEYASDIFYYLRELEVKYR 223

  Fly   220 PKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTA 284
            |.|.||:.|.:::...|..:|||||::...::|..|||||::..:|||||:..|..::.||||.:
Yeast   224 PNPYYMQNQVELTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVS 288

  Fly   285 AMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDM 349
            |::||||:|||..|.:.:.|::.:::||:..::|.||.::..|.|::..|....|:...:...|.
Yeast   289 ALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDY 353

  Fly   350 PEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEI-----TTYKLE 409
            ..:.:.:..|:.|.:::|.: .:...||.:::.:..|:|.|||...|:  |:.:     |:.::.
Yeast   354 DFEPRTLAKYLLETTIVEPK-LVAAAPSWLAAGAYFLSRTILGSNDWS--LKHVFYSGYTSSQII 415

  Fly   410 DLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVAMMESVEMSKDDFDQLCEAYNCKQKEDE 473
            .|.:::|..|   |.|         .:.:...:||.            |||  :.|.|.|..:|
Yeast   416 PLASLILENC---KNA---------SRRHHSIWKKY------------FDQ--KHYRCSQIVEE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	52/125 (42%)
		Cyclin_C	334..450	CDD:281044	23/120 (19%)
CLB4	NP_013311.1	COG5024	10..459	CDD:227357	127/519 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I1327
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X94
TreeFam	0	0.000	Not matched by this tool.
	6	5.710