DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and CYCA3;3

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_175155.1	Gene:	CYCA3;3 / 841125	AraportID:	AT1G47220	Length:	327	Species:	Arabidopsis thaliana

Alignment Length:	254	Identity:	104/254 - (40%)
Similarity:	162/254 - (63%)	Gaps:	11/254 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 YQMDILEYFRESEKKHRPKPL--YMRR-QKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYL 264
            |..||.||.||.|.|.:.:||  |:.: |:||:.:.|.:|:||||||:||::|.:|||||:|.|:
plant    56 YVSDIYEYLRELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLVEVAEEFELVSETLYLTVSYI 120

  Fly   265 DRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSF 329
            |||||...|....|||||.:||:||:||||...|:|.:|.::|.::|||..||:||:.||..|.|
plant   121 DRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFCYITANTYTKQDVLKMEEDILLALEF 185

  Fly   330 DLCTPTAYVFINTYAVLCDMPEKLKYMTL-----YISELSLMEGETYLQYLPSLMSSASVALARH 389
            :|..||...|:..:..:.....|:..:.|     |:||||::: .:.::::|||:::::|.|||.
plant   186 ELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCYLSELSMLD-YSCVKFVPSLLAASAVFLARF 249

  Fly   390 IL--GMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVA 446
            |:  ....|:..|||.|.||..||:..|..:...:.:..|..::|:||||.:..::.||
plant   250 IILPNQHPWSQMLEECTKYKAADLQVCVEIMLDLYLSRSEGASKAVREKYKQHKFQYVA 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	66/128 (52%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	36/120 (30%)
CYCA3;3	NP_175155.1	CYCLIN_AtCycA_like_rpt1	49..186	CDD:410265	66/129 (51%)
CYCA3;3	NP_175155.1	CYCLIN_AtCycA-like_rpt2	190..304	CDD:410210	34/114 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1564
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I1366
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	1	1.000	-	-		otm3250
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870