DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and CYCD3;3

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_190576.1	Gene:	CYCD3;3 / 824169	AraportID:	AT3G50070	Length:	361	Species:	Arabidopsis thaliana

Alignment Length:	216	Identity:	52/216 - (24%)
Similarity:	97/216 - (44%)	Gaps:	39/216 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 RSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSK---LQLVGTAAMYIAAKYEEIYP 297
            |...:||:.:|...|..::.|..|:|.|.|||::.......|   .||...|.:.:|||.|||..
plant    86 REKALDWIFKVKSHYGFNSLTALLAVNYFDRFITSRKFQTDKPWMSQLTALACLSLAAKVEEIRV 150

  Fly   298 PEVGEFVFLTDDSYTKAQ-------VLRMEQVILKILSFDL--CTPTAYV--FINTYAVLCDMPE 351
            |      ||.|....:|:       :.|||.::|..|.:.:  .||.::.  .|..|:.
plant   151 P------FLLDFQVEEARYVFEAKTIQRMELLVLSTLDWRMHPVTPISFFDHIIRRYSF------ 203

  Fly   352 KLKYMTLYISE-----LSLMEGETYLQYLPSLMSSA-SVALARHILGMEMWTPRLEEITTYKLED 410
            |..:...::|.     ||::....:|.:.||::::| .|::.|.:...:....:.:.:|..|::.
plant   204 KSHHQLEFLSRCESLLLSIIPDSRFLSFSPSVLATAIMVSVIRDLKMCDEAVYQSQLMTLLKVDS 268

  Fly   411 LKTVVLHLCH----THKTAKE 427
            .|   ::.|:    .|..:|:
plant   269 EK---VNKCYELVLDHSPSKK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	32/107 (30%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	19/106 (18%)
CYCD3;3	NP_190576.1	CYCLIN_AtCycD-like_rpt1	85..183	CDD:410246	32/102 (31%)
CYCD3;3	NP_190576.1	CYCLIN_AtCycD-like_rpt2	188..278	CDD:410247	18/98 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010