DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and CYCB1;3

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_187759.2	Gene:	CYCB1;3 / 820325	AraportID:	AT3G11520	Length:	414	Species:	Arabidopsis thaliana

Alignment Length:	439	Identity:	128/439 - (29%)
Similarity:	199/439 - (45%)	Gaps:	70/439 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRN 73
            |:.|......:....:.|....:.|.|||              ||      ||.        .||
plant    18 DLKNAAAKNRRALGDIGNVDSLIGVEGGK--------------LN------RPI--------TRN 54

  Fly    74 LNVD--ENVEYGAKKSNVVPVVE-----QFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFG 131
            ....  ||.:..|..:...|:::     |....:|.:.....:..||......::..:.::|...
plant    55 FRAQLLENAQVAAAANKKAPILDGVTKKQEVVRAVQKKARGDKREPSKPIEVIVISPDTNEVAKA 119

  Fly   132 AGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQR 196
            ...|:.|.|.      ||.|.:|                      ...|.|..:..:...||
plant   120 KENKKKVTYS------SVLDARS----------------------KAASKTLDIDYVDKEND--- 153

  Fly   197 FLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSV 261
             |..|:|..|:..:::|...:.:|: :||..|.:|...||||||||||||..::.|..|||||:|
plant   154 -LAAVEYVEDMYIFYKEVVNESKPQ-MYMHTQPEIDEKMRSILIDWLVEVHVKFDLSPETLYLTV 216

  Fly   262 FYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKI 326
            ..:|||||...|.|.:|||||.:|:.||:|||||:||:|.:.|::||:||...|:|.||:.||..
plant   217 NIIDRFLSLKTVPRRELQLVGVSALLIASKYEEIWPPQVNDLVYVTDNSYNSRQILVMEKTILGN 281

  Fly   327 LSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHIL 391
            |.:.|..||.|||:..:.......:||:.:..:::||.||..:: |.:.||::::::|..||..|
plant   282 LEWYLTVPTQYVFLVRFIKASGSDQKLENLVHFLAELGLMHHDS-LMFCPSMLAASAVYTARCCL 345

  Fly   392 G-MEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNR 439
            . ...||..|:..|.|....|......|...|..|.|...:.:.:||::
plant   346 NKTPTWTDTLKFHTGYSESQLMDCSKLLAFIHSKAGESKLRGVLKKYSK 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	61/125 (49%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	30/107 (28%)
CYCB1;3	NP_187759.2	Cyclin_N	162..287	CDD:278560	61/125 (49%)
CYCB1;3	NP_187759.2	Cyclin_C	289..406	CDD:281044	30/107 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820