Protein Alignment CycA and CCNI2

DIOPT Version :9

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001274181.1
• Gene: CCNI2 / 645121
• HGNCID: 33869
• Length: 385
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 83/384 - (21%)
• Similarity: 137/384 - (35%)
• Gaps: 112/384 - (29%)

  Fly   142 LDSTPMS--VTDVQSP-----MSVDRSILGV-------------------------------IQS 168
            |...|.|  |:.||||     ..::.:.|||                               ..|
Human     7 LPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLHAAS 71

  Fly   169 SDISVGTETGVSPTGRV---------KELP--------PRN-----DRQRFLEVVQYQMDILEYF 211
            :.:.|....|.:|.|:.         ::.|        |||     |.:|.|..:|...|
Human    72 AAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDERRLLCHLQLAQD----- 131

  Fly   212 RESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRS 276
            ||:......||     |.:|......::: ||:.:...:.....|..|::....|.|..:.|...
Human   132 REARLWRGGKP-----QDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEK 190

  Fly   277 KLQLVGTAAMYIAAKY--EEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLC--TPTAY 337
            .|......::.:|||.  ||.:.|:|.:|.......|:..::||||..||..|.:||.  ||..:
Human   191 YLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDF 255

  Fly   338 VFINTYAVLC----------------DMPEKLKYM-----TLYISELS-----LMEGETYLQYLP 376
            :.|..|.|.|                ..|..|:.:     :|:::.|:     .|.|...||:..
Human   256 LTIEKYGVFCSNIKNHGLQFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLLQFKG 320

  Fly   377 SLMSSASVALARHILGMEMW-TPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMR 434
            |.::...:.|....| |..| .|..:.:...::.|::         :...|||..|.:|
Human   321 STLALVIITLELERL-MPGWCAPISDLLKKAQVGDMQ---------YSCCKELVMQQLR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	32/127 (25%)
		Cyclin_C	334..450	CDD:281044	25/128 (20%)
CCNI2	NP_001274181.1	Cyclin_N	<156..247	CDD:278560	24/90 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740