DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and Ccnd1

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_008758390.1	Gene:	Ccnd1 / 58919	RGDID:	68384	Length:	317	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	61/218 - (27%)
Similarity:	112/218 - (51%)	Gaps:	32/218 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 NDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMR-RQKDISHNMRSILIDWLVEVSEEYKLDTE 255
            |||            :|....::|:...|...|.: .|::|..:||.|:..|::||.||.|.:.|
  Rat    24 NDR------------VLRAMLKTEETCAPSVSYFKCVQREIVPSMRKIVATWMLEVCEEQKCEEE 76

  Fly   256 TLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRME 320
            ...|::.|||||||...:.:|:|||:|...|::|:|.:|..|....:....||:|....::|:||
  Rat    77 VFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQME 141

  Fly   321 QVILKILSFDLCTPTAYVFINTYAVLCDMPEK-------LKYMTLYISELSLMEGETYLQYL--- 375
            .:::..|.::|...|.:.||..:  |..|||.       .|:...:::..:     |.::::
  Rat   142 LLLVNKLKWNLAAMTPHDFIEHF--LSKMPEADENKQIIRKHAQTFVALCA-----TDVKFISNP 199

  Fly   376 PSLMSSASVALARHILGMEMWTP 398
            ||::::.||..|  :.|:.:.:|
  Rat   200 PSMVAAGSVVAA--MQGLNLGSP 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	41/126 (33%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	16/75 (21%)
Ccnd1	XP_008758390.1	Cyclin_N	31..153	CDD:278560	40/121 (33%)
Ccnd1	XP_008758390.1	Cyclin_C	156..291	CDD:281044	16/74 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840