DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and Ccng1

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_037055.1	Gene:	Ccng1 / 25405	RGDID:	2295	Length:	294	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	58/235 - (24%)
Similarity:	110/235 - (46%)	Gaps:	23/235 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 DRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHN-------MRSILIDWLVEVSEEY 250
            |.|:.|    :|::.|   .|.|.:.:||...::..:....|       :|...:..|:.:::.:
  Rat     8 DSQKLL----HQLNTL---LEQESRCQPKVCGLKLIESAHDNGLRMTARLRDFEVKDLLSLTQFF 65

  Fly   251 KLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAK--YEEIYPPEVGEFVFLTDDSYTK 313
            ..||||..|:|..||||||:|.|....|..||.:..|:|.|  .||...|...:.:.::...:|.
  Rat    66 GFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTV 130

  Fly   314 AQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSL 378
            :.::|||:::|:.:.:.:...||:.|:..|..|  :.|.|.:..........:|.:....:...:
  Rat   131 SDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSL--IRETLPFERRNDLNFERLEAQLKACHCRII 193

  Fly   379 MSSASVA-LARHILGMEMWTPRLEEITTYKLEDLKTVVLH 417
            .|.|..: ||..|:.:|:...:..|:|    |.::.:..|
  Rat   194 FSKAKPSVLALAIIALEIQALKYVELT----EGVECIQKH 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	36/134 (27%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	18/85 (21%)
Ccng1	NP_037055.1	CYCLIN_CCNG1	50..147	CDD:410286	30/96 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740