DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycA and Ccno

DIOPT Version :9

Sequence 1:	NP_524030.2	Gene:	CycA / 39340	FlyBaseID:	FBgn0000404	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001074531.1	Gene:	Ccno / 218630	MGIID:	2145534	Length:	352	Species:	Mus musculus

Alignment Length:	292	Identity:	83/292 - (28%)
Similarity:	136/292 - (46%)	Gaps:	41/292 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 DLDSTPMSVTD-VQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQ 204
            ||..:|.|.:| ..||        .|..:.|.|    :.::|...:..|    |.|.|.|   |.
Mouse    59 DLFESPSSSSDGADSP--------AVSAARDCS----SLLNPAQPLTAL----DLQTFRE---YG 104

  Fly   205 MDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLS 269
            ....::.:..|....|:. .:.||..::...|..|:.||::|..::.|..|:|.|:|..|||||.
Mouse   105 QSCYDFRKAQENLFHPRE-SLARQPQVTAESRCKLLSWLLQVHRQFGLSFESLCLTVNTLDRFLL 168

  Fly   270 QMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTP 334
            ...|.....||:|...:.||.|..|::||.:.:.:.|...::::.|:..:|.::|..|.|.|..|
Mouse   169 TTPVAADCFQLLGVTCLLIACKQVEVHPPRLKQLLALCGGAFSRQQLCNLECIVLHKLHFSLGAP 233

  Fly   335 TAYVFINTY------AVLCDMPEKLKYMTLY--ISELSLMEGETYLQYLPSLMSSASVALA---- 387
            |...|:..:      |...::.|.|:..||.  ::||||.: ..:..|.||||:...:|||
Mouse   234 TINFFLEHFTQWRMEAGQAEVTEALEAQTLARGVAELSLTD-YAFTTYTPSLMAICCLALADGLL 297

  Fly   388 RHILGMEMWTPRLEEITTYKLED----LKTVV 415
            :|...|::   ||.|.....|:|    |:|:|
Mouse   298 QHQHEMDL---RLGEHPEATLQDCLGKLQTLV 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	35/125 (28%)
CycA	NP_524030.2	Cyclin_C	334..450	CDD:281044	30/98 (31%)
Ccno	NP_001074531.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		Cyclin_N	108..231	CDD:278560	35/123 (28%)
		Cyclin_C	233..>301	CDD:281044	21/68 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810