Protein Alignment CycA and Ccna2

DIOPT Version :9

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_033958.2
• Gene: Ccna2 / 12428
• MGIID: 108069
• Length: 422
• Species: Mus musculus
• Alignment Length: 467
• Identity: 173/467 - (37%)
• Similarity: 251/467 - (53%)
• Gaps: 79/467 - (16%)

  Fly     2 ASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALA--PRANFAVLNGNNNVPRPAGK 64
            |...:||:.....||                      ||.|.|  |||...:..||...|.|..|
Mouse    15 ALLSLHQEDQENVNP----------------------EKLAPAQQPRAQAVLKAGNVRGPAPQQK 57

  Fly    65 VQVFR--DVRNLNV-DENVEYGAKKSNVVPVVEQFKTFSVYEDN-NDTQVAPSGKSLASLVDKEN 125
            ::..|  .:::|.: ||:|..|....    .|.:...|:::.|. .:||..|     |.|.:.|.
Mouse    58 LKTRRVAPLKDLPINDEHVTAGPSWK----AVSKQPAFTIHVDEAEETQKRP-----AELKETEC 113

  Fly   126 HD-------VKFGAGQKEL--VDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSP 181
            .|       |.....:|.|  :||.:|.:      .:||.::|.||  |::...::|.
Mouse   114 EDALAFNAAVSLPGARKPLTPLDYPMDGS------FESPHAMDMSI--VLEDKPVNVN------- 163

  Fly   182 TGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEV 246
                             ||..||.||..|.||.|.|.:||..||:||.||:::||:||:||||||
Mouse   164 -----------------EVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEV 211

  Fly   247 SEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSY 311
            .|||||..|||:|:|.|:|||||.|:|:|.||||||||||.:|:|:||||||||.|||::|||:|
Mouse   212 GEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY 276

  Fly   312 TKAQVLRMEQVILKILSFDLCTPTAYVFINTYAV-LCDMPEKLKYMTLYISELSLMEGETYLQYL 375
            :|.||||||.::||:|:|||..||...|:..|.: |.....|::.:.:::.||||::.:.||:||
Mouse   277 SKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYL 341

  Fly   376 PSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRD 440
            |||::.|:..||.:.:..:.|...|.:.|.|.||.||..::.|..|:..|.:...|::||||...
Mouse   342 PSLIAGAAFHLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHS 406

  Fly   441 TYKKVAMMESVE 452
            .|..|:::...|
Mouse   407 KYHSVSLLNPPE 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	83/125 (66%)
		Cyclin_C	334..450	CDD:281044	38/116 (33%)
Ccna2	NP_033958.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62		17/68 (25%)
		Cyclin_N2	22..152	CDD:293109	39/166 (23%)
		Cyclin_N	171..297	CDD:278560	83/125 (66%)
		Cyclin_C	299..417	CDD:281044	38/117 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	179	1.000	Domainoid score	I3516
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55562
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3178
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	1	1.000	-	-		otm42820
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4504
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.850