Protein Alignment CycA and CCNO

DIOPT Version :9

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_066970.3
• Gene: CCNO / 10309
• HGNCID: 18576
• Length: 350
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 78/281 - (27%)
• Similarity: 128/281 - (45%)
• Gaps: 30/281 - (10%)

  Fly   155 PMSVDRSILGVIQS-SDISVGTET-----GVSPTGRVKELPPRNDRQRFLEVVQ--YQMDILEYF 211
            |:..|..|..:.:| |..|.|.|:     |.||.....:...:.|.|.|.:..|  |.      |
Human    50 PLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYA------F 108

  Fly   212 RESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRS 276
            |::::.|......:.||..::...|..|:.||:.|..::.|..|:|.|:|..|||||:...|...
Human   109 RKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAAD 173

  Fly   277 KLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFIN 341
            ..||:|..::.||.|..|::||.|.:.:.|...::::.|:..:|.::|..|.|.|..||...|:.
Human   174 CFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLE 238

  Fly   342 TY------AVLCDMPEKLKYMTLY--ISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTP 398
            .:      |...:..|.|:...|.  ::||||.: ..:..|.|||::...:|||..:|
Human   239 HFTHARVEAGQAEASEALEAQALARGVAELSLAD-YAFTSYSPSLLAICCLALADRML------- 295

  Fly   399 RLEEITTYKLEDLKTVVLHLC 419
            |:......:|.|.....|..|
Human   296 RVSRPVDLRLGDHPEAALEDC 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	37/125 (30%)
		Cyclin_C	334..450	CDD:281044	24/94 (26%)
CCNO	NP_066970.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..89		11/38 (29%)
		Cyclin_N	108..229	CDD:278560	37/120 (31%)
		Cyclin_C	231..>296	CDD:281044	19/72 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810